Qasim Haider, Simpson Maree, Guisard Yann, de Courten Barbora
School of Biomedical Science, Charles Sturt University, Orange 2800, NSW, Australia.
Faculty of Science, Charles Sturt University, Orange 2800, NSW, Australia.
Pharmacy (Basel). 2020 Mar 31;8(2):56. doi: 10.3390/pharmacy8020056.
this scoping review was designed to identify studies that assess adverse drug reactions (ADRs) for older people in Australian aged care facilities. This review critically evaluates each published study to identify the risk of, or actual, adverse drug events in older people. Inclusion criteria: this review considered any clinical studies that examined the adverse effects of medications in older people who were living in aged care facilities. This review considered qualitative studies, analytical studies, randomized controlled trials (RCTs), descriptive cross-sectional studies, and analytic observational studies that explored the use of medications and their adverse effects on older people in clinical settings (including aged care facilities). an initial search of the PubMed (United State National Library of Medicine), OvidSP, EBSCOHost, ScienceDirect, Wiley Online, SAGE, and SCOPUS databases, with full text was performed, followed by an analysis of the article's title and abstract. Additionally, MeSH (Medical Subject Headings) was used to describe the article. The initial round of the database search was based on inclusion criteria from studies that assessed tools or protocols aiming to identify the adverse effects of medications on the elderly population suffering chronic conditions or multiple co-morbidities. Two reviewers screened the retrieved papers for inclusion. The data presented in this review are in tabular forms and accompanied by a narrative summary which aligns with the review's objectives. seven studies were identified, and the extracted data from these studies were grouped according their characteristics and the auditing results of each study. it would be beneficial to design a comprehensive or broadly adverse drug reaction assessment tool derived from Australian data that has been used on the elderly in an Australian healthcare setting.
本范围综述旨在识别评估澳大利亚老年护理机构中老年人药物不良反应（ADR）的研究。本综述对每项已发表的研究进行严格评估，以确定老年人中不良药物事件的风险或实际情况。纳入标准：本综述考虑了任何检查居住在老年护理机构中的老年人药物不良反应的临床研究。本综述考虑了定性研究、分析性研究、随机对照试验（RCT）、描述性横断面研究以及探索临床环境（包括老年护理机构）中药物使用及其对老年人不良反应的分析性观察研究。首先对美国国立医学图书馆的PubMed、OvidSP、EBSCOHost、ScienceDirect、Wiley Online、SAGE和SCOPUS数据库进行了全文检索，随后对文章标题和摘要进行了分析。此外，使用医学主题词（MeSH）来描述文章。第一轮数据库检索基于评估旨在识别药物对患有慢性病或多种合并症的老年人群不良反应的工具或方案的研究纳入标准。两名评审员筛选检索到的论文以确定是否纳入。本综述中呈现的数据以表格形式呈现，并伴有与综述目标一致的叙述性总结。共识别出七项研究，并根据这些研究的特征和每项研究的审核结果对提取的数据进行分组。设计一种基于澳大利亚数据的、用于澳大利亚医疗保健环境中老年人的全面或广泛的药物不良反应评估工具将是有益的。
