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纺织材料的生物功能化。2. 磷霉素对聚丙交酯(PLA)无纺布的抗菌改性

Biofunctionalization of Textile Materials. 2. Antimicrobial Modification of Poly(lactide) (PLA) Nonwoven Fabricsby Fosfomycin.

作者信息

Kudzin Marcin H, Mrozińska Zdzisława

机构信息

The Lukasiewicz Research Network -Textile Research Institute, Brzezinska 5/15, 92-103 Lodz, Poland.

出版信息

Polymers (Basel). 2020 Apr 1;12(4):768. doi: 10.3390/polym12040768.

Abstract

This research is focused on obtaining antimicrobial hybrid materials consisting of poly(lactide) nonwoven fabrics and using phosphoro-organic compound-fosfomycin-as a coating and modifying agent. Polylactide (PLA) presents biodegradable polymer with multifunctional application, widely engaged in medical related areas. Fosfomycin as functionalized phosphonates presents antibiotic properties expressed by broad spectrum of antimicrobial properties. The analysis of these biofunctionalized nonwoven fabrics processed by the melt-blown technique, included: scanning electron microscopy (SEM), UV/VIS transmittance, FTIR spectrometry, air permeability. The functionalized nonwovens were tested on microbial activity tests against colonies of gram-positive () and gram-negative() bacteria.

摘要

本研究聚焦于制备由聚丙交酯无纺布组成的抗菌杂化材料,并使用有机磷化合物——磷霉素作为涂层和改性剂。聚丙交酯(PLA)是一种具有多功能应用的可生物降解聚合物,广泛应用于医疗相关领域。磷霉素作为功能化膦酸盐具有抗生素特性,表现出广谱抗菌性能。对这些通过熔喷技术加工的生物功能化无纺布进行的分析包括:扫描电子显微镜(SEM)、紫外/可见透光率、傅里叶变换红外光谱(FTIR)以及透气率。对功能化无纺布进行了针对革兰氏阳性菌和革兰氏阴性菌菌落的微生物活性测试。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ca7/7240420/a4a61428b087/polymers-12-00768-g001.jpg

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