磁控溅射金属化法制备棉锌复合材料及其抗菌性能和细胞毒性评估

Preparation of Cotton-Zinc Composites by Magnetron Sputtering Metallization and Evaluation of their Antimicrobial Properties and Cytotoxicity.

作者信息

Kudzin Marcin Henryk, Giełdowska Małgorzata, Król Paulina, Sobańska Zuzanna

机构信息

Łukasiewicz Research Network-Łódz Institute of Technology, 19/27 Marii Sklodowskiej-Curie Str., 90-570 Łódz, Poland.

Nofer Institute of Occupational Medicine, Św. Teresy od Dzieciątka Jezus 8, 91-348 Łódz, Poland.

出版信息

Materials (Basel). 2022 Apr 8;15(8):2746. doi: 10.3390/ma15082746.

DOI:10.3390/ma15082746

PMID:35454445

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9026216/

Abstract

The aim of this investigation was to evaluate the biological properties of cotton-zinc composites. A coating of zinc (Zn) on a cotton fabric was successfully obtained by a DC magnetron sputtering system using a metallic Zn target (99.9%). The new composite was characterized using scanning electron microscopy/energy-dispersive X-ray spectroscopy (SEM/EDS), UV/Vis transmittance, and atomic absorption spectrometry with flame excitation (FAAS). The composite was tested for microbial activity against colonies of Gram-positive () and Gram-negative () bacteria and antifungal activity against and fungal mold species as model microorganisms. Cytotoxicity screening of the tested modified material was carried out on BALB/3T3 clone mouse fibroblasts. The SEM/EDS and FAAS tests showed good uniformity of zinc content on a large surface of the composite. The conducted research showed the possibility of using the magnetron sputtering technique as a zero-waste method for producing antimicrobial textile composites.

摘要

本研究的目的是评估棉-锌复合材料的生物学特性。使用金属锌靶材（99.9%）通过直流磁控溅射系统成功地在棉织物上获得了锌（Zn）涂层。采用扫描电子显微镜/能量色散X射线光谱仪（SEM/EDS）、紫外/可见透光率以及火焰激发原子吸收光谱法（FAAS）对新型复合材料进行了表征。以革兰氏阳性（）和革兰氏阴性（）细菌菌落为模型微生物，测试了该复合材料的抗菌活性，并以和真菌霉菌为模型微生物测试了其抗真菌活性。在BALB/3T3克隆小鼠成纤维细胞上对测试的改性材料进行了细胞毒性筛选。SEM/EDS和FAAS测试表明复合材料大表面上锌含量具有良好的均匀性。所进行的研究表明，磁控溅射技术作为一种零废物生产抗菌纺织复合材料的方法具有可行性。