a Department of Epidemiology , School of Public Health, Shandong University , Jinan , China.
b Division of Biology , The High School Affiliated To Shandong University , Jinan , China.
Hum Vaccin Immunother. 2018 Feb 1;14(2):404-411. doi: 10.1080/21645515.2017.1393132. Epub 2017 Dec 1.
Willingness to be vaccinated with human papillomavirus (HPV) vaccine among junior middle school students in China is not well understood. We conducted a cross-sectional study to assess awareness of HPV and the HPV vaccine and explore the factors associated with willingness to be vaccinated.
First-year students from two junior middle schools in Jinan, China were selected by cluster sampling on December 28, 2015, December 26, 2016, and January 11, 2017, and a self-administered questionnaire was used to collect information. Multivariate logistic regression was conducted to explore the factors associated with willingness to be vaccinated with the HPV vaccine.
A total of 1021 junior middle school students participated in this survey. Only 15.5% of them had heard of HPV and 18.9% of them had heard of the HPV vaccine. Students who were willing to take the HPV vaccine in the future accounted for 66.9%. Factors associated with the HPV vaccination were: urban junior middle school students (AOR: 1.51, 95% CI: 1.09-2.09), female students (AOR: 1.90, 95% CI: 1.36-2.66), students surveyed in 2015 (AOR: 1.69, 95% CI: 1.26-2.28), regarding menstruation/spermatorrhoea as a normal physiological phenomenon (AOR: 1.64, 95% CI: 1.14-2.36), believing vaccination is an important way to prevent diseases (AOR: 1.36, 95% CI: 1.01-1.83), believing that the first vaccination should be in infancy (AOR: 1.41, 95% CI: 1.04-1.92), believing that cervical cancer is a concern for themselves (AOR: 1.95, 95% CI: 1.28-2.97), and having heard of HPV (AOR: 1.84, 95% CI: 1.13-2.98).
Awareness of HPV and the HPV vaccine among junior students was low, however willingness to be vaccinated was high. Education focusing on HPV-related knowledge in addition to sex education is needed to promote the coverage of the HPV vaccine.
中国初中生对人乳头瘤病毒（HPV）疫苗接种的意愿尚未得到充分了解。本研究旨在评估 HPV 及 HPV 疫苗的认知情况，并探讨与接种意愿相关的因素。
采用整群抽样的方法，于 2015 年 12 月 28 日、2016 年 12 月 26 日和 2017 年 1 月 11 日，选取济南两所初中的初一学生进行问卷调查。采用多因素 logistic 回归分析方法，探索 HPV 疫苗接种意愿的相关因素。
共纳入 1021 名初中生，仅有 15.5%的学生听说过 HPV，18.9%的学生听说过 HPV 疫苗。66.9%的学生表示未来愿意接种 HPV 疫苗。多因素分析结果显示，城市初中生（OR：1.51，95%CI：1.09-2.09）、女生（OR：1.90，95%CI：1.36-2.66）、2015 年调查的学生（OR：1.69，95%CI：1.26-2.28）、将月经/遗精视为正常生理现象（OR：1.64，95%CI：1.14-2.36）、认为接种疫苗是预防疾病的重要手段（OR：1.36，95%CI：1.01-1.83）、认为首次接种应在婴幼儿时期（OR：1.41，95%CI：1.04-1.92）、认为宫颈癌是自身健康问题（OR：1.95，95%CI：1.28-2.97）、听说过 HPV（OR：1.84，95%CI：1.13-2.98）的学生更愿意接种 HPV 疫苗。
初中生对 HPV 及 HPV 疫苗的认知程度较低，但接种意愿较高。除性教育外，还应加强 HPV 相关知识教育，以提高 HPV 疫苗的接种率。
