Jelnes R, Bülow J, Tønnesen K H, Lassen N A, Holstein P
Dept of Surgery M, Bispebjerg Hospital, Copenhagen, Denmark.
Eur J Vasc Surg. 1988 Feb;2(1):31-3. doi: 10.1016/s0950-821x(88)80104-x.
Adipose tissue blood flow in the forefoot was measured simultaneously with mean systemic arterial blood pressure over 24 hours in 8 patients (15 feet) with different degrees of arterial insufficiency. Mean systemic arterial pressure decreased by 19 +/- 9% during sleep, irrespective of symptomatology. In two limbs, with a normal peripheral circulation, blood flow decreased by 8 +/- 7%. In five limbs with arterial insufficiency, but no rest pain, blood flow decreased by 16 +/- 8% and in eight limbs with ischaemic nocturnal rest pain blood flow was reduced by 32 +/- 12% during sleep. It is concluded that nocturnal hypotension is a major factor in the production of nocturnal ischaemic rest pain.
对8例（15只脚）不同程度动脉供血不足的患者，在24小时内同时测量前足的脂肪组织血流量和平均体动脉血压。无论症状如何，睡眠期间平均体动脉压下降19±9%。在两个外周循环正常的肢体中，血流量下降8±7%。在五个有动脉供血不足但无静息痛的肢体中，血流量下降16±8%，而在八个有缺血性夜间静息痛的肢体中，睡眠期间血流量减少32±12%。结论是夜间低血压是夜间缺血性静息痛产生的主要因素。
