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同期颈动脉支架置入术和心脏手术的中期结果。

Midterm Results After Simultaneous Carotid Artery Stenting and Cardiac Surgery.

机构信息

Department of Cardiac Surgery, Dedinje Cardiovascular Institute, Belgrade, Serbia.

Department of Cardiac Surgery, Dedinje Cardiovascular Institute, Belgrade, Serbia; School of Medicine, University of Belgrade, Belgrade, Serbia.

出版信息

Ann Thorac Surg. 2020 Nov;110(5):1557-1563. doi: 10.1016/j.athoracsur.2020.02.051. Epub 2020 Apr 2.

Abstract

BACKGROUND

The presence of carotid artery disease is known risk factor for perioperative stroke in cardiac surgery. The optimal management of patients with concomitant heart and carotid artery disease is not known. Simultaneous or staged carotid endarterectomy has been proposed to prevent stroke. In an attempt to reduce perioperative morbidity and death, simultaneous carotid stenting and cardiac surgery were implemented (hybrid procedure). This study evaluated early and midterm results after the hybrid procedure.

METHODS

From November 2012 through November 2018, 54 patients (36 men; an average age, 65.8 ± 7.3 years) underwent the hybrid procedure. The primary end points were the occurrence of perioperative cerebral stroke, transient ischemic attack (TIA), acute myocardial infarction, bleeding, or death. The mean follow-up period was 30 months.

RESULTS

The 30-day mortality was 0%. Periprocedural incidence of stroke and transient ischemic attack were 1.9% and 7.6%, respectively, and acute myocardial infarction occurred in 1 patient (1.9%). No patients required repeat thoracotomy for bleeding. Four patients (7.6%) died during follow-up. The cause of death was stroke in 2 patients (3.8%), heart failure in 1 (1.9%), and multiorgan failure in 1 (1.9%). In-stent restenosis of the carotid artery occurred in 1 patient (1.9%).

CONCLUSIONS

In this small group of patients, the hybrid procedure proved to be a safe and efficient treatment for patients with concomitant carotid and cardiac diseases. The low rate of perioperative complications and good midterm results are encouraging.

摘要

背景

颈动脉疾病的存在是心脏手术围手术期中风的已知危险因素。同时患有心脏和颈动脉疾病的患者的最佳治疗方法尚不清楚。已经提出同时或分期颈动脉内膜切除术以预防中风。为了降低围手术期发病率和死亡率,已经实施了同时颈动脉支架置入术和心脏手术(杂交手术)。本研究评估了杂交手术后的早期和中期结果。

方法

从 2012 年 11 月至 2018 年 11 月,54 例患者(36 名男性;平均年龄 65.8±7.3 岁)接受了杂交手术。主要终点是围手术期脑中风、短暂性脑缺血发作(TIA)、急性心肌梗死、出血或死亡的发生。平均随访时间为 30 个月。

结果

30 天死亡率为 0%。围手术期中风和短暂性脑缺血发作的发生率分别为 1.9%和 7.6%,1 例患者(1.9%)发生急性心肌梗死。没有患者因出血需要再次开胸。4 例患者(7.6%)在随访期间死亡。死亡原因是 2 例患者(3.8%)中风,1 例(1.9%)心力衰竭和 1 例(1.9%)多器官衰竭。1 例(1.9%)患者颈动脉支架内再狭窄。

结论

在这一小组患者中,杂交手术被证明是一种安全有效的治疗同时患有颈动脉和心脏疾病的方法。低并发症发生率和良好的中期结果令人鼓舞。

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