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单孔机器人辅助根治性前列腺切除术:初步经验的系统评价和汇总分析。

Single-port robot-assisted radical prostatectomy: a systematic review and pooled analysis of the preliminary experiences.

机构信息

Department of Urology, San Luigi Gonzaga Hospital, University of Turin, Turin, Italy.

Division of Urology, VCU Health, Richmond, VA, USA.

出版信息

BJU Int. 2020 Jul;126(1):55-64. doi: 10.1111/bju.15069. Epub 2020 May 1.

Abstract

OBJECTIVE

To summarize the clinical experiences with single-port (SP) robot-assisted radical prostatectomy (RARP) reported in the literature and to describe the peri-operative and short-term outcomes of this procedure.

MATERIAL AND METHODS

A systematic review of the literature was performed in December 2019 using Medline (via PubMed), Embase (via Ovid), Cochrane databases, Scopus and Web of Science (PROSPERO registry number 164129). All studies that reported intra- and peri-operative data on SP-RARP were included. Cadaveric series and perineal or partial prostatectomy series were excluded.

RESULTS

The pooled mean operating time, estimated blood loss, length of hospital stay and catheterization time were 190.55 min, 198.4 mL, 1.86 days and 8.21 days, respectively. The pooled mean number of lymph nodes removed was 8.33, and the pooled rate of positive surgical margins was 33%. The pooled minor complication rate was 15%. Only one urinary leakage and one major complication (transient ischaemic attack) were recorded. Regarding functional outcomes, pooled continence and potency rates at 12 weeks were 55% and 42%, respectively.

CONCLUSIONS

The present analysis confirms that SP-RARP is safe and feasible. This novel robotic platform resulted in similar intra-operative and peri-operative outcomes to those obtained with the standard multiport da Vinci system. The advantages of single incision can be translated into a preservation of the patient's body image and self-esteem and cosmesis, which have a great impact on a patient's quality of life.

摘要

目的

总结文献中报道的单孔(SP)机器人辅助根治性前列腺切除术(RARP)的临床经验,并描述该手术的围手术期和短期结果。

材料和方法

2019 年 12 月,我们通过 Medline(通过 PubMed)、Embase(通过 Ovid)、Cochrane 数据库、Scopus 和 Web of Science(PROSPERO 注册号 164129)进行了文献系统性回顾。纳入了所有报告 SP-RARP 术中及围手术期数据的研究。排除了尸体研究和会阴或部分前列腺切除术系列。

结果

汇总的平均手术时间、估计失血量、住院时间和导尿时间分别为 190.55 分钟、198.4 毫升、1.86 天和 8.21 天。汇总的平均淋巴结切除数为 8.33 个,阳性手术切缘率为 33%。汇总的轻微并发症发生率为 15%。仅记录到 1 例尿漏和 1 例主要并发症(短暂性脑缺血发作)。关于功能结果,12 周时汇总的控尿率和勃起功能率分别为 55%和 42%。

结论

目前的分析证实 SP-RARP 是安全可行的。这种新型机器人平台的术中及围手术期结果与标准多孔达芬奇系统相当。单切口的优势可以转化为对患者身体形象和自尊的保护,以及对患者生活质量有重大影响的美容效果。

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