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远视性小切口微透镜取出术后眼压变化和角膜生物力学。

Intraocular pressure changes and corneal biomechanics after hyperopic small-incision lenticule extraction.

机构信息

Department of Ophthalmology, Eye and ENT Hospital of Fudan University, No. 83 FenYang Road, Shanghai, 200031, China.

NHC Key Laboratory of Myopia (Fudan University), Shanghai, China.

出版信息

BMC Ophthalmol. 2020 Apr 5;20(1):129. doi: 10.1186/s12886-020-01384-2.

Abstract

BACKGROUND

We aimed to compare the intraocular pressure (IOP) measurements by a dynamic Scheimpflug analyzer (Corvis ST), a non-contact tonometer, and an ocular response analyzer after hyperopic small-incision lenticule extraction (SMILE).

METHODS

Thirteen patients who underwent hyperopic SMILE in one eye were enrolled prospectively. IOP and corneal biomechanical parameters were measured preoperatively and at 1 week, 1 month, and 3 months postoperatively with a non-contact tonometer (IOP), Corvis ST (biomechanical corrected IOP [bIOP]), and ocular response analyzer (Goldmann-correlated intraocular pressure [IOPg] and cornea compensated IOP [IOPcc]). A linear mixed model was used to compare the IOPs and biomechanical values among methods at each time point.

RESULTS

IOP, IOPg, and IOPcc dropped significantly after surgery, with the amplitude being 3.15 ± 0.48 mmHg, 5.49 ± 0.94 mmHg, and 4.34 ± 0.97 mmHg, respectively, at the last follow-up visit. IOP decreased by 0.11 ± 0.06 mmHg per μm of excised central corneal thickness. bIOP did not change significantly after surgery. Preoperatively, no difference was found among the four measurements (P > 0.05). Postoperatively, IOP and bIOP were higher than IOPg and IOPcc. bIOP was independent of cornea thickness at last follow-up visit, whereas it correlated significantly with corneal biomechanics similar to the other three IOP values.

CONCLUSION

bIOP is a relative accurate measure of IOP after hyperopic SMILE.

摘要

背景

本研究旨在比较远视性小切口透镜切除术(SMILE)后动态 Scheimpflug 分析仪(Corvis ST)、非接触眼压计和眼反应分析仪测量的眼压(IOP)。

方法

前瞻性纳入 13 例单眼接受远视性 SMILE 手术的患者。术前及术后 1 周、1 个月和 3 个月分别使用非接触眼压计(IOP)、Corvis ST(生物力学校正眼压[bIOP])和眼反应分析仪(Goldmann 相关眼压[IOPg]和角膜补偿眼压[IOPcc])测量 IOP 和角膜生物力学参数。采用线性混合模型比较各方法在各时间点的 IOP 和生物力学值。

结果

术后 IOP、IOPg 和 IOPcc 显著降低,末次随访时降幅分别为 3.15±0.48mmHg、5.49±0.94mmHg 和 4.34±0.97mmHg。每切除 1μm 中央角膜厚度,IOP 降低 0.11±0.06mmHg。术后 bIOP 无显著变化。术前四项测量值之间无差异(P>0.05)。术后 IOP 和 bIOP 高于 IOPg 和 IOPcc。bIOP 与角膜厚度在末次随访时无相关性,与其他三种 IOP 值一样与角膜生物力学显著相关。

结论

bIOP 是远视性 SMILE 术后 IOP 的相对准确测量值。

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