新型 Corvis ST 眼压测量值与中央角膜厚度和角膜滞后量的关系。

Relationship between novel intraocular pressure measurement from Corvis ST and central corneal thickness and corneal hysteresis.

机构信息

Department of Ophthalmology, University of Tokyo, Tokyo, Japan.

Department of Ophthalmology, Graduate school of Medical Science, Kitasato University, Sagamihara, Kanagawa, Japan.

出版信息

Br J Ophthalmol. 2020 Apr;104(4):563-568. doi: 10.1136/bjophthalmol-2019-314370. Epub 2019 Jul 30.

DOI:10.1136/bjophthalmol-2019-314370

PMID:31362932

Abstract

AIMS

Corvis ST (CST) yields biomechanical corrected IOP (bIOP) which is purported to be less dependent on biomechanical properties. In our accompanied paper, it was suggested that the repeatability of bIOP is high. The purpose of the current study was to assess the relationship between intraocular pressure (IOP) measured with CST and central corneal thickness (CCT) and corneal hysteresis (CH), in comparison with IOP measured with Goldmann applanation tonometry (GAT) and the ocular response analyzer (ORA).

METHODS

A total of 141 eyes from 141 subjects (35 healthy eyes and 106 glaucomatous eyes) underwent IOP measurements with GAT, CST and ORA. The relationships between IOP measurements (ORA-IOPg, ORA-IOPcc, CST-bIOP and GAT IOP) and biomechanical properties (CCT, CH and corneal resistance factor (CRF)) were analysed using the linear regression analysis.

RESULTS

IOPg, IOPcc and GAT IOP were significantly associated with CCT (p<0.001), whereas bIOP was not significantly associated with CCT (p=0.19). IOPg, bIOP and GAT IOP were significantly associated with CH (IOPg: p<0.001; bIOP: p<0.001; GAT IOP: p=0.0054), whereas IOPcc was not significantly associated with CH (p=0.18). All of IOP records were associated with CRF (p<0.001).

CONCLUSION

The bIOP measurement from CST is independent from CCT, but dependent on CH and CRF.

摘要

目的

Corvis ST（CST）可提供生物力学校正的眼压（bIOP），据称其对生物力学特性的依赖性较低。在我们的相关论文中，已经表明 bIOP 的重复性较高。本研究的目的是评估 CST 测量的眼压（IOP）与中央角膜厚度（CCT）和角膜滞后量（CH）之间的关系，并与 Goldmann 压平眼压计（GAT）和眼反应分析仪（ORA）测量的眼压进行比较。

方法

共有 141 名受试者（35 名健康眼和 106 名青光眼眼）的 141 只眼接受了 GAT、CST 和 ORA 的眼压测量。使用线性回归分析评估了眼压测量值（ORA-IOPg、ORA-IOPcc、CST-bIOP 和 GAT IOP）与生物力学特性（CCT、CH 和角膜阻力因子（CRF））之间的关系。

结果

IOPg、IOPcc 和 GAT IOP 与 CCT 显著相关（p<0.001），而 bIOP 与 CCT 无显著相关性（p=0.19）。IOPg、bIOP 和 GAT IOP 与 CH 显著相关（IOPg：p<0.001；bIOP：p<0.001；GAT IOP：p=0.0054），而 IOPcc 与 CH 无显著相关性（p=0.18）。所有眼压记录均与 CRF 相关（p<0.001）。