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种植前垂直骨缺损中自体骨移植与异种骨植入的安全性和有效性比较及初步临床数据

Preliminary Clinical Data and the Comparison of the Safety and Efficacy of Autogenous Bone Grafts Versus Xenograft Implantations in Vertical Bone Deficiencies Before Dental Implant Installation.

作者信息

Wychowanski Piotr, Woliński Jarosław, Morawiec Tadeusz, Kownacki Patryk, Starzynska Anna, Kosieradzki Maciej, Fiedor Piotr

机构信息

Department of Oral Surgery, Medical University of Warsaw, Warsaw, Poland; Specialized Private Implantology Clinic Wychowanski Stomatologia, Warsaw, Poland.

Department of Animal Physiology, the Kielanowski Institute of Animal Physiology and Nutrition, Polish Academy of Sciences, Jabłonna, Poland.

出版信息

Transplant Proc. 2020 Sep;52(7):2248-2251. doi: 10.1016/j.transproceed.2020.02.099. Epub 2020 Apr 3.

DOI:10.1016/j.transproceed.2020.02.099
PMID:32252999
Abstract

Two different techniques of vertical bone augmentation were compared to apply them to immunocompromised patients. One of them used autogenous bone graft; the other used xenograft. Thirty patients were involved in the study. Fifteen received autogenous ring shape grafts harvested from the mental region, and 15 received xenograft vertical tunnel augmentation. They have a total of 60 implants placed in the posterior region of the mandible (2 for each patient). Fixed full ceramic crowns were delivered. Two-year follow-up appointments after implant placement were made. Both autogenous bone grafts and xenografts showed similar long-term clinical regeneration outcome of vertical bone defects. Using autogenous bone rings simultaneously fixed by dental implants, the total treatment time and cost were shortened, but the traumatic reactions and complication rates were higher when compared to xenograft vertical tunnel augmentation. Due to the less traumatic character of the procedure, smaller complication rates and higher safety for the patients receiving chronic immunosuppression should avoid bone block augmentation and reap the benefits from vertical tunnel bone augmentation using xenograft materials.

摘要

比较了两种不同的垂直骨增量技术,以将其应用于免疫功能低下的患者。其中一种使用自体骨移植;另一种使用异种移植物。30名患者参与了该研究。15名患者接受了从颏部采集的自体环形移植物,15名患者接受了异种移植物垂直隧道增量术。他们在下颌骨后部共植入了60颗种植体(每位患者2颗)。安装了固定全瓷冠。在种植体植入后进行了两年的随访预约。自体骨移植和异种移植物在垂直骨缺损的长期临床再生结果方面显示相似。使用由牙种植体同时固定的自体骨环,总治疗时间和成本缩短,但与异种移植物垂直隧道增量术相比,创伤反应和并发症发生率更高。由于该手术创伤较小,并发症发生率较低,对于接受慢性免疫抑制的患者,更高的安全性应避免骨块增量,并从使用异种移植材料的垂直隧道骨增量术中获益。

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Preliminary Clinical Data and the Comparison of the Safety and Efficacy of Autogenous Bone Grafts Versus Xenograft Implantations in Vertical Bone Deficiencies Before Dental Implant Installation.种植前垂直骨缺损中自体骨移植与异种骨植入的安全性和有效性比较及初步临床数据
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2
The role of collagen and crystallinity in the physicochemical properties of naturally derived bone grafts.胶原蛋白和结晶度在天然骨移植材料物理化学性质中的作用。
Regen Biomater. 2024 Aug 14;11:rbae093. doi: 10.1093/rb/rbae093. eCollection 2024.
3
Efficacy of bone ring grafts for the reconstruction of alveolar ridge deficiencies: A systematic review. Part I: Clinical trials.
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Medicine (Baltimore). 2024 Mar 15;103(11):e37471. doi: 10.1097/MD.0000000000037471.
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Implants Placed with a Ring Technique Using Inlay and Onlay Block Xenografts in the Mandible of Rabbits.采用嵌体和覆盖块异种移植物的环形技术在下颌骨植入兔体内。
Materials (Basel). 2023 Dec 3;16(23):7490. doi: 10.3390/ma16237490.
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