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一种用于磁性纳米粒子多功能生物功能化的超分子方法。

A supramolecular approach for versatile biofunctionalization of magnetic nanoparticles.

作者信息

Hu Changming, Wu Jingxian, Wei Ting, Zhan Wenjun, Qu Yangcui, Pan Yue, Yu Qian, Chen Hong

机构信息

State and Local Joint Engineering Laboratory for Novel Functional Polymeric Materials, College of Chemistry, Chemical Engineering and Materials Science, Soochow University, 199 Ren'ai Road, Suzhou, 215123, P. R. China.

出版信息

J Mater Chem B. 2018 Apr 21;6(15):2198-2203. doi: 10.1039/c8tb00490k. Epub 2018 Apr 5.

DOI:10.1039/c8tb00490k
PMID:32254561
Abstract

A convenient and versatile approach for biofunctionalization of magnetic nanoparticles (MNPs) was developed based on supramolecular host-guest interaction. Adamantane groups were introduced on the surface of MNPs for further incorporation of specific biofunctional β-cyclodextrin derivatives, endowing MNPs with the desired bioactivity (e.g. biorecognition capability and biocidal activity).

摘要

基于超分子主客体相互作用,开发了一种便捷通用的磁性纳米颗粒(MNPs)生物功能化方法。在MNPs表面引入金刚烷基团,以便进一步结合特定的生物功能β-环糊精衍生物,赋予MNPs所需的生物活性(如生物识别能力和杀菌活性)。

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