College of Polymer Science and Engineering, Sichuan University, Chengdu, 610065, China.
J Mater Chem B. 2019 Jan 28;7(4):509-527. doi: 10.1039/c8tb02812e. Epub 2019 Jan 3.
Bone-related diseases seriously threaten people's health and research studies have been dedicated towards searching for new and effective treatment methods. Nanotechnologies have opened up a new field in recent decades and nanostructured materials, which exist in a variety of forms, are considered to be promising materials in this field. This article reviews the most recent progress in the development of nanostructured materials for bone-related diseases, including osteoporosis, osteoarthritis, bone metastasis, osteomyelitis, myeloma, and bone defects. We highlight the advantages and functions of nanostructured materials, including sustained release, bone targeting, scaffolding in bone tissue engineering, etc., in bone-related diseases. We also include the remaining challenges of these emerging materials.
骨相关疾病严重威胁着人们的健康，因此人们致力于研究新的、有效的治疗方法。近几十年来，纳米技术开辟了一个新的领域，各种形式的纳米结构材料被认为是该领域有前途的材料。本文综述了纳米结构材料在骨相关疾病（包括骨质疏松症、骨关节炎、骨转移、骨髓炎、骨髓瘤和骨缺损）方面的最新研究进展。我们强调了纳米结构材料在骨相关疾病中的优势和功能，包括缓释、骨靶向、骨组织工程支架等。我们还包括这些新兴材料所面临的挑战。
