儿童视神经炎后的恢复情况。
Recovery after optic neuritis in childhood.
作者信息
Kriss A, Francis D A, Cuendet F, Halliday A M, Taylor D S, Wilson J, Keast-Butler J, Batchelor J R, McDonald W I
机构信息
Hospital for Sick Children, London, UK.
出版信息
J Neurol Neurosurg Psychiatry. 1988 Oct;51(10):1253-8. doi: 10.1136/jnnp.51.10.1253.
Abstract
Thirty-nine children who presented with optic neuritis in childhood were reviewed after a follow up period from 3 months to 29 years (mean 8.8 years). At follow-up, 30 out of 39 (77%) of the children had had no further episodes and in three (8%) there was recurrence of optic neuritis alone. Multiple sclerosis had developed in six patients (15%), a much lower frequency than after optic neuritis in adult life. Regardless of the initial degree of visual impairment or neurological outcome, the visual prognosis was excellent. Pattern evoked potentials at follow-up were much more frequently normal (55%) than in adults (10%) after optic neuritis.
摘要
对39例儿童期出现视神经炎的患儿进行了随访，随访时间为3个月至29年（平均8.8年）。随访时，39例患儿中有30例（77%）未再出现发作，3例（8%）仅出现视神经炎复发。6例患者（15%）发生了多发性硬化，这一频率远低于成人期视神经炎后的发生率。无论初始视力损害程度或神经学转归如何，视力预后均良好。随访时图形诱发电位正常的频率（55%）远高于成人视神经炎后的频率（10%）。
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