Samanta Soumen K, Isaacs Lyle
Department of Chemistry and Biochemistry, University of Maryland, College Park, Maryland 20742 United States.
School of Chemistry, University of Bristol, Cantock's Close, United Kingdom, BS8 1TS.
Coord Chem Rev. 2020 May 15;410. doi: 10.1016/j.ccr.2020.213181. Epub 2020 Feb 19.
Since the discovery and structural characterization of metal organic polygons and polyhedra (), scientists have explored their potential in various applications like catalysis, separation, storage, and sensing. In recent years, scientists have explored the potential of supramolecular in biomedical application. Pioneering works by Ehrlich, Rosenberg, Lippard, Stang and others have demonstrated that have great potential as a novel class of metallo-therapeutics that can deliver cargoes (drugs and dyes) selectively. In this article, we document the progress made over the past two decades on the biomedical applications of and discuss the future prospects of this emerging field.
自从金属有机多边形和多面体被发现并进行结构表征以来，科学家们一直在探索它们在催化、分离、存储和传感等各种应用中的潜力。近年来，科学家们还探索了超分子在生物医学应用中的潜力。埃利希、罗森伯格、利帕德、斯坦格等人的开创性工作表明，超分子作为一类新型金属治疗剂具有巨大潜力，能够选择性地输送货物（药物和染料）。在本文中，我们记录了过去二十年来超分子在生物医学应用方面取得的进展，并讨论了这一新兴领域的未来前景。
