Katibeh Pegah, Inaloo Soroor, Jafari Peyman, Fattah Fahimeh, Mazloomi Samaneh
Department of Pediatric Neurology, Shiraz University of Medical Sciences, Shiraz, Iran.
Department of Biostatics, Shiraz University of Medical Sciences, Shiraz, Iran.
Iran J Child Neurol. 2020 Spring;14(2):59-68.
People suffering from chronic diseases like epilepsy are highly prone to debilitating changes in factors that affect the quality of life (QOL) such as physical capacity, self-esteem, relationships with others and fulfillment of their daily life activities. This study attempted to evaluate QOL in children with epilepsy in Shiraz, Southern Iran.
MATERIALS & METHODS: Epileptic patients admitted at the epilepsy clinic of Shiraz University of Medical Sciences with no first time episode of seizures in the previous six months and no febrile-seizure were included in the study. The patients were evaluated using the standard KIDSCREEN-27 questionnaire. Data were analyzed using the statistical software SPSS 21 along with Man Whitney and Chi-square tests, and were reported in terms of descriptive statistics. The significance level was considered less than 0.05.
In this case-control study, 229 children with epilepsy were compared with a control group of 400 normal individuals. The mean age was 12.44±3.16 and 12.10±2.69 years in the case and control groups, respectively. The tonic-clonic seizure had the highest prevalence. Moreover, male gender, older age and more seizures per year were associated with lower QOL. Overall, epileptic children had significantly lower QOL compared to the controls.
Epileptic children have an overall lower QOL while factors such as old age, male gender, and high number of seizures per year reduce QOL in epileptic patients.
患有癫痫等慢性病的人极易在影响生活质量(QOL)的因素上出现使人衰弱的变化,如身体能力、自尊、与他人的关系以及日常生活活动的完成情况。本研究试图评估伊朗南部设拉子癫痫患儿的生活质量。
纳入设拉子医科大学癫痫门诊收治的癫痫患者,这些患者在过去六个月内没有首次发作癫痫且没有热性惊厥。使用标准的儿童生活质量量表(KIDSCREEN-27)对患者进行评估。使用统计软件SPSS 21以及曼-惠特尼检验和卡方检验对数据进行分析,并以描述性统计的形式报告。显著性水平设定为小于0.05。
在这项病例对照研究中,将229名癫痫患儿与400名正常个体组成的对照组进行比较。病例组和对照组的平均年龄分别为12.44±3.16岁和12.10±2.69岁。强直阵挛发作的患病率最高。此外,男性、年龄较大以及每年发作次数较多与较低的生活质量相关。总体而言,癫痫患儿的生活质量明显低于对照组。
癫痫患儿的总体生活质量较低,而年龄较大、男性以及每年发作次数较多等因素会降低癫痫患者的生活质量。