Anu M, Suresh K, Basavanna P L
Postgraduate Student, Department of Pharmacology, MMC & RI (Mysore Medical College and Research Institute) , Mysuru, Karnataka, India .
Associate Professor, Department of Neurology, MMC & RI (Mysore Medical College and Research Institute) , Mysuru, Karnataka, India .
J Clin Diagn Res. 2016 Dec;10(12):OC13-OC15. doi: 10.7860/JCDR/2016/23151.8979. Epub 2016 Dec 1.
Epilepsy is a chronic disorder associated with profound physical and psychological consequences leading to impaired quality of life (QoL). Evaluation of the QoL among epileptics would throw light on various factors that impair or affect the QoL in such a population.
To study the QoL among epileptic patients attending outpatient departments of a tertiary care hospital and to identify various factors that affect the QoL in such a population.
A cross-sectional observational questionnaire based study, including patients with epilepsy, who were on antiepileptic drugs, on follow-up for minimum one year, aged more than 18years, both sexes and who were seizure free in the previous 24hours. The World Health Organisation Quality of Life (WHOQOL-BREF) questionnaire was administered to those included in the study. The data was analysed using Statistical Package for Social Sciences (SPSS) version 20 and statistical tests like t-test for independent variables and Analysis of Variance (ANOVA) were used to compare the QoL scores.
Of the 98 subjects 61.2% were males, majority were educated upto high school level and most of them were employed in unskilled labour. The mean total QOL score was 53.9 (15.8). There was a significant lower mean total QOL score among people with low educational status and poor seizure control.
Epilepsy is a syndrome associated with chronic drug use and regular long term follow-ups to hospitals. These treatment and disease associated problems affects the QOL of the subjects significantly in various squares of life. We found that a lower education and having seizure in the recent past affected the QOL scores.
癫痫是一种慢性疾病，会带来严重的身体和心理后果，导致生活质量（QoL）受损。评估癫痫患者的生活质量将有助于了解影响该人群生活质量的各种因素。
研究在一家三级护理医院门诊部就诊的癫痫患者的生活质量，并确定影响该人群生活质量的各种因素。
一项基于横断面观察问卷的研究，纳入正在服用抗癫痫药物、至少随访一年、年龄超过18岁、男女不限且在过去24小时内无癫痫发作的癫痫患者。对纳入研究的患者发放世界卫生组织生活质量（WHOQOL-BREF）问卷。使用社会科学统计软件包（SPSS）20版对数据进行分析，并使用独立变量的t检验和方差分析（ANOVA）等统计检验来比较生活质量得分。
在98名受试者中，61.2%为男性，大多数人接受的教育程度为高中水平，他们中的大多数从事非技术劳动工作。生活质量总平均得分为53.9（15.8）。教育程度低和癫痫控制不佳的人群的生活质量总平均得分显著较低。
癫痫是一种与长期用药和定期到医院进行长期随访相关的综合征。这些与治疗和疾病相关的问题在生活的各个方面都对受试者的生活质量产生了重大影响。我们发现，较低的教育程度和近期有癫痫发作会影响生活质量得分。
