Honari Bahareh, Homam Seyed Mehran, Nabipour Maryam, Mostafavian Zahra, Farajpour Arezou, Sahbaie Nyusha
Faculty of Psychology and Educational Sciences, Semnan University, Semnan, Iran.
Department of Neurology, Mashhad Branch, Islamic Azad University, Mashhad, Iran.
J Patient Rep Outcomes. 2021 Jan 28;5(1):16. doi: 10.1186/s41687-021-00292-3.
Epilepsy is one of the most common neurological disorders with physical, emotional, and social consequences. Previous studies indicate that epilepsy symptoms can highly affect the epileptic patients' satisfaction in life. The aim of the present study is to investigate the QOL of People with Epilepsy (PWE) in Khorasan Razavi province, Iran.
In this study, 100 patients were randomly selected. After confirmation of the diagnosis of epilepsy by neurologists and fulfilling the entrance criteria, patients completed the Quality of Life in Epilepsy-31 inventory (QOLIE-31) questionnaire. Finally, data was analyzed statistically by SPSS software.
The study sample comprised 100 PWE, aged 18-74 years (34 ± 13), of whom 58 (58%) were females. Tonic-colonic seizure was the most common (60%) type of seizure. The obtained score of each subscale and the range of the QOLIE-31 total score was 16.40-79.18 with the mean of 50 (SD = 16). The energy-fatigue subscale score was significantly higher in patients younger than 35 (p = 0.018). The data analysis showed that the seizure worry subscale was significantly higher in single patients (p = 0.04). Duration of epilepsy had a positive correlation with QOLIE-31 total score (p = 0.038), and a negative relationship with energy-fatigue subscale (p = 0.018). In contrast with previous studies, which reported the frequency of the epileptic episodes as the most important predictor of QOL, our results showed no significant correlation between the number of the episodes and overall QOL score (p = 0.063). However, the number of episodes was significantly correlated with emotional well-being and cognition subscales. Furthermore, the results indicated that poor QOL score is correlated with depressed mood.
In fact, the ultimate and preferred outcome of all treatments and care interventions is the patient's QOL. Thus, improvement of the QOL by means of obtaining more information about its contributing factors, in PWE should be one of the main goals in the patients' treatment.
癫痫是最常见的神经系统疾病之一，会对身体、情感和社会产生影响。先前的研究表明，癫痫症状会极大地影响癫痫患者的生活满意度。本研究的目的是调查伊朗霍拉桑拉扎维省癫痫患者的生活质量。
本研究随机选取了100名患者。在神经科医生确诊癫痫并满足入选标准后，患者完成癫痫生活质量-31量表（QOLIE-31）问卷。最后，使用SPSS软件对数据进行统计分析。
研究样本包括100名癫痫患者，年龄在18 - 74岁之间（34 ± 13岁），其中58名（58%）为女性。强直阵挛发作是最常见的发作类型（60%）。每个子量表的得分以及QOLIE-31总分范围为16.40 - 79.18，平均分为50分（标准差 = 16）。35岁以下患者的精力-疲劳子量表得分显著更高（p = 0.018）。数据分析表明，单身患者的发作担忧子量表得分显著更高（p = 0.04）。癫痫病程与QOLIE-31总分呈正相关（p = 0.038），与精力-疲劳子量表呈负相关（p = 0.018）。与先前将癫痫发作频率作为生活质量最重要预测因素的研究不同，我们的结果显示发作次数与总体生活质量得分之间无显著相关性（p = 0.063）。然而，发作次数与情绪健康和认知子量表显著相关。此外，结果表明生活质量得分低与情绪低落相关。
事实上，所有治疗和护理干预的最终和理想结果是患者的生活质量。因此，通过获取更多关于影响癫痫患者生活质量因素的信息来改善生活质量，应是患者治疗的主要目标之一。
