Coelho Sara, Magalhães Helena, Correia Jorge, Magalhães Adriana, Lourenço Patrícia
Internal Medicine Department, Centro Hospitalar São João, E.P.E., Oporto, Portugal.
Medical Oncology Department, Instituto Português de Oncologia, E.P.E., Oporto, Portugal.
Porto Biomed J. 2017 May-Jun;2(3):93-95. doi: 10.1016/j.pbj.2017.01.007. Epub 2017 Feb 22.
Polymyalgia rheumatica is an inflammatory rheumatologic condition that occurs frequently in the elderly. It has been, although infrequently, associated with malignancies, in a synchronous or closely time-related appearance. In such circumstances, polymyalgia rheumatica is considered to be a paraneoplastic syndrome and is often atypical in presentation with poor response to glucocorticoid treatment. We report the case of a 79-year-old woman in which the simultaneous diagnosis of polymyalgia rheumatica and lung adenocarcinoma was made. Rheumatologic symptoms responded partially to anti-inflammatory medication, with further response to lung cancer targeted chemotherapy.
风湿性多肌痛是一种常见于老年人的炎症性风湿性疾病。它虽然不常见,但与恶性肿瘤以同步或时间密切相关的形式出现有关。在这种情况下,风湿性多肌痛被认为是一种副肿瘤综合征,其表现通常不典型,对糖皮质激素治疗反应不佳。我们报告了一例79岁女性患者,该患者同时被诊断为风湿性多肌痛和肺腺癌。风湿性症状对抗炎药物部分有效,对肺癌靶向化疗有进一步反应。