Rodrigues Pedro, Ferreira Tiago, Nascimento-Gonçalves Elisabete, Seixas Fernanda, Gil da Costa Rui Miguel, Martins Tânia, Neuparth Maria João, Pires Maria João, Lanzarin Germano, Félix Luís, Venâncio Carlos, Ferreira Isabel C F R, Bastos Margarida M S M, Medeiros Rui, Gaivão Isabel, Rosa Eduardo, Oliveira Paula A
Centre for the Research and Technology of Agro-Environmental and Biological Sciences (CITAB), UTAD, 5000-801 Vila Real, Portugal.
Department of Veterinary Sciences and Animal and Veterinary Research Centre (CECAV), University of Trás-os-Montes and Alto Douro (UTAD), Quinta de Prados, 5000-801 Vila Real, Portugal.
Biomedicines. 2020 Apr 4;8(4):75. doi: 10.3390/biomedicines8040075.
The production of chestnut ( Miller) is mostly concentrated in Europe. Chestnut is recognized by its high content of antioxidants and phytosterols. This work aimed to evaluate the effects of dietary chestnut consumption over physiological variables of FVB/n mice. Eighteen FVB/n male 7-month-old mice were randomly divided into three experimental groups ( = 6): 1 (control group) fed a standard diet; 2 fed a diet supplemented with 0.55% (/) chestnut; and 3 supplemented with 1.1% (/) chestnut. Body weight, water, and food intake were recorded weekly. Following 35 days of supplementation, the mice were sacrificed for the collection of biological samples. Chestnut supplementation at 1.1% reduced abdominal adipose tissue. Lower serum cholesterol was also observed in animals supplemented with chestnut. There were no significant differences concerning the incidence of histological lesions nor in biochemical markers of hepatic damage and oxidative stress. These results suggest that chestnut supplementation may contribute to regulate adipose tissue deposition.
板栗（ 米勒）的产量大多集中在欧洲。板栗因其高含量的抗氧化剂和植物甾醇而闻名。这项工作旨在评估食用板栗对FVB/n小鼠生理变量的影响。18只7月龄的FVB/n雄性小鼠被随机分为三个实验组（ = 6）：1组（对照组）喂食标准饮食；2组喂食添加了0.55%（/）板栗的饮食；3组添加1.1%（/）板栗。每周记录体重、饮水量和食物摄入量。在补充35天后，处死小鼠以收集生物样本。补充1.1%的板栗可减少腹部脂肪组织。在补充板栗的动物中也观察到血清胆固醇降低。在组织学病变的发生率以及肝损伤和氧化应激的生化标志物方面没有显著差异。这些结果表明，补充板栗可能有助于调节脂肪组织沉积。
