Mele E
Department of Materials, Loughborough University, LE11 3TU, Loughborough, UK.
J Mater Chem B. 2016 Jul 28;4(28):4801-4812. doi: 10.1039/c6tb00804f. Epub 2016 Jun 27.
In the last few years, the health-care services have registered worldwide an increased number of patients suffering from chronic wounds and ulcers, which are mainly associated with diabetes, obesity and cancer. The need for regenerating rapidly and effectively the injured skin has stimulated the research of advanced therapies for wound care. This review will discuss how biomimetic architectures produced by electrospinning natural biopolymers fulfil most of the requirements of ideal wound dressings. It will also examine the recent progress in the area of portable electrospinning systems and of multiscale instructive materials that integrate stimuli responsive and sensing elements.
在过去几年中，全球医疗保健服务领域中患有慢性伤口和溃疡的患者数量有所增加，这些病症主要与糖尿病、肥胖症和癌症相关。快速有效地再生受损皮肤的需求推动了伤口护理先进疗法的研究。本综述将讨论通过静电纺丝天然生物聚合物制备的仿生结构如何满足理想伤口敷料的大部分要求。还将研究便携式静电纺丝系统以及集成了刺激响应和传感元件的多尺度指导性材料领域的最新进展。
