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电纺聚合物纳米纤维在改善伤口愈合方面的生物医学应用的最新研究综述。

Review of recent research on biomedical applications of electrospun polymer nanofibers for improved wound healing.

机构信息

Materials Science & Technology Program, College of Arts & Sciences, Qatar University, Doha 2713, Qatar.

Biomedical Research Center, Qatar University, Doha 2713, Qatar.

出版信息

Nanomedicine (Lond). 2016 Mar;11(6):715-37. doi: 10.2217/nnm.15.211. Epub 2016 Jan 8.

Abstract

Wound dressings play an important role in a patient's recovery from health problems, as unattended wounds could lead to serious complications such as infections or, ultimately, even death. Therefore, wound dressings since ancient times have been continuously developed, starting from simple dressings from natural materials for covering wounds to modern dressings with functionalized materials to aid in the wound healing process and enhance tissue repair. However, understanding the nature of a wound and the subsequent healing process is vital information upon which dressings can be tailored to ensure a patient's recovery. To date, much progress has been made through the use of nanomedicine in wound healing due to the ability of such materials to mimic the natural dimensions of tissue. This review provides an overview of recent studies on the physiology of wound healing and various wound dressing materials made of nanofibers fabricated using the electrospinning technique.

摘要

伤口敷料在患者从健康问题中恢复的过程中起着重要的作用,因为未处理的伤口可能导致严重的并发症,如感染,甚至最终导致死亡。因此,自古以来,伤口敷料一直在不断发展,从用于覆盖伤口的天然材料的简单敷料到具有功能化材料的现代敷料,以帮助伤口愈合过程并增强组织修复。然而,了解伤口的性质和随后的愈合过程是至关重要的信息,敷料可以根据这些信息进行定制,以确保患者的康复。迄今为止,由于纳米材料能够模拟组织的自然尺寸,因此在伤口愈合中使用纳米医学已经取得了很大的进展。本综述提供了对伤口愈合生理学和使用静电纺丝技术制造的各种纳米纤维伤口敷料材料的最新研究的概述。

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