Green D W, Ben-Nissan B, Yoon Kyung-Sik, Milthorpe B, Jung H-S
Oral Biosciences, Faculty of Dentistry, The University of Hong Kong, Sai Ying Pun, Hong Kong SAR, China.
J Mater Chem B. 2016 Apr 14;4(14):2396-2406. doi: 10.1039/c5tb02634b. Epub 2016 Feb 18.
The evolution of life has given rise to innumerable biomaterials with high levels of functional sophistication and performance among many thousands of different environments. The inexhaustible range of strategies and the intrinsic good design they possess can be readily included in the design of biomedical devices and materials, such as wound healing bandages and antibacterial surface coating implants. We highlight topical examples where various ingenious design strategies from biological models, originating more broadly from zoology and botany, have been appropriated into novel synthetic materials and structures for regenerative and material-based tissue engineering. Bioinspired materials engineering informed and enriched by the vast array of adaptations and strategies in nature, beyond human biology, will be instrumental in the future evolution of new more clinically acceptable pan-functional materials and structures with a broad range of uses in the regenerative sciences.
生命的演化在数以千计的不同环境中催生了无数具有高度复杂功能和卓越性能的生物材料。它们拥有无穷无尽的策略以及内在的优良设计，这些都可以轻松地应用于生物医学设备和材料的设计中，比如伤口愈合绷带和抗菌表面涂层植入物。我们重点介绍一些典型例子，在这些例子中，源自动物学和植物学等更广泛领域的生物模型中的各种巧妙设计策略，已被应用于新型合成材料和结构中，用于再生和基于材料的组织工程。受自然界中大量适应性和策略启发的材料工程，超越了人类生物学范畴，将有助于未来开发出更多临床上可接受的泛功能材料和结构，这些材料和结构在再生科学领域有着广泛的用途。
