Centro de Formação de Professores, Universidade Federal do Recôncavo da Bahia, Amargosa, BA, Brasil.
Departamento de Ciências do Esporte, Instituto de Ciências da Saúde, Universidade Federal do Triângulo Mineiro, Uberaba, MG, Brasil.
Braz J Med Biol Res. 2020 Apr 6;53(4):e9200. doi: 10.1590/1414-431X20209200. eCollection 2020.
The consumption of alcoholic beverages influences carbohydrate and lipid metabolism, although it is not yet clear whether metabolism during physical exercise at different intensities is also affected. This was the objective of the present study. Eight young and healthy volunteers performed a treadmill test to identify the running speed corresponding to a lactate concentration of 4 mM (S4mM). At least 48 h later, they were subjected to two experimental trials (non-alcohol or alcohol) in which they performed two 1-km running sessions at the following intensities: 1) S4mM; 2) 15% above S4mM. In both trials, blood lactate, triglycerides, and glucose concentrations were measured before and after exercise. The acute alcohol intake increased triglycerides, but not lactate concentration under resting conditions. Interestingly, alcohol intake enhanced the exercise-induced increase in lactate concentration at the two intensities: S4mM (non-alcohol: 4.2±0.3 mM vs alcohol: 4.8±0.9 mM; P=0.003) and 15% above S4mM trial (P=0.004). When volunteers ingested alcohol, triglycerides concentration remained increased after treadmill running (e.g., at S4mM - at rest; non-alcohol: 0.2±0.5 mM vs alcohol: 1.3±1.3 mM; P=0.048). In contrast, glucose concentration was not modified by either alcohol intake, exercise, or their combination. We concluded that an acute alcohol intake changed lactate and lipid metabolism without affecting blood glucose concentration. In addition, the increase in lactate concentration caused by alcohol was specifically observed when individuals exercised, whereas augmented triglycerides concentration was already observed before exercise and was sustained thereafter.
饮酒会影响碳水化合物和脂质代谢，尽管目前尚不清楚不同强度的运动期间代谢是否也会受到影响。这就是本研究的目的。
8 名年轻健康的志愿者进行了跑步机测试，以确定乳酸浓度为 4mM（S4mM）时的跑步速度。至少 48 小时后，他们进行了两项实验性试验（非酒精或酒精），在这些试验中，他们以以下强度进行了两次 1 公里跑步：1）S4mM；2）S4mM 以上 15%。在这两项试验中，运动前后均测量了血乳酸、甘油三酯和葡萄糖浓度。急性饮酒会增加休息时的甘油三酯，但不会增加血乳酸浓度。有趣的是，酒精摄入增强了两种强度下运动引起的血乳酸浓度升高：S4mM（非酒精：4.2±0.3mM 与酒精：4.8±0.9mM；P=0.003）和 S4mM 以上 15%试验（P=0.004）。当志愿者饮酒时，甘油三酯浓度在跑步机跑步后仍保持升高（例如，在 S4mM 时-休息时；非酒精：0.2±0.5mM 与酒精：1.3±1.3mM；P=0.048）。相比之下，酒精摄入、运动或两者的组合均不影响血糖浓度。
我们得出结论，急性饮酒会改变乳酸和脂质代谢，而不会影响血糖浓度。此外，酒精引起的乳酸浓度增加仅在个体运动时观察到，而升高的甘油三酯浓度在运动前已经观察到，并在此后持续存在。
