Behaviour and Health Research Unit, University of Cambridge, UK.
Addiction. 2020 Dec;115(12):2280-2292. doi: 10.1111/add.15042. Epub 2020 Apr 8.
To assess the impact of purchasing wine in 50 cl bottles compared with 75 cl bottles on the amount of wine consumed at home.
Cross-over randomized controlled trial with a 'usual behaviour' period of a maximum of 3 weeks between conditions.
Households in the United Kingdom.
One hundred and eighty-six households that consumed between two and eight 75 cl bottles of wine each week.
Households were randomized to the order in which they purchased wine in two bottle sizes. During two 14-day intervention periods, households purchased a pre-set volume of wine-based on their baseline self-reported weekly consumption-in either 75 cl bottles or 50 cl bottles. On days 7 and 14 of each study period, participating households sent photographs of each purchased wine bottle.
The primary outcome was the volume of study wine in millilitres (ml) consumed during each study period estimated through returned photographs. The secondary outcome was the rate of consumption measured by the mean number of days taken to drink 1.5 litres from each bottle size.
One hundred and sixty-six of 186 enrolled households satisfactorily completed the study. After accounting for pre-specified covariates, 191.1 ml [95% confidence interval (CI) = 42.03-339.2] or 4.5% (95% CI = 1.0-7.9%) more wine was consumed per 14-day period from 75-cl bottles than from 50-cl bottles. Consumption was 5.8% faster (95% CI = -10.9 to -0.4%) from 75 cl bottles than from 50 cl bottles.
Consuming wine at home from 50 cl bottles, compared with 75 cl bottles, may reduce both amount consumed and rate of consumption.
评估在家中饮用 50 毫升和 75 毫升瓶装葡萄酒对饮酒量的影响。
交叉随机对照试验，条件之间的“常规行为”期最长为 3 周。
英国的家庭。
186 个每周饮用 2 至 8 瓶 75 毫升装葡萄酒的家庭。
家庭随机分配购买两种瓶型的顺序。在两个为期 14 天的干预期内，根据其基线自我报告的每周饮酒量，家庭购买预先设定量的基于葡萄酒的饮料-在 75 毫升或 50 毫升的瓶子中。在每个研究期的第 7 天和第 14 天，参与家庭发送每个购买的酒瓶照片。
主要结局是通过退回的照片估计的每个研究期内消耗的研究葡萄酒的毫升数（ml）。次要结局是通过两种瓶型的平均饮酒天数来衡量的消耗率。
186 名入组家庭中有 166 名家庭满意地完成了研究。在考虑到预先指定的协变量后，与 50 毫升瓶相比，75 毫升瓶每 14 天期间多消耗 191.1 毫升（95%置信区间（CI）= 42.03-339.2）或 4.5%（95% CI= 1.0-7.9%）的葡萄酒。从 75 毫升瓶消耗的速度快 5.8%（95% CI= -10.9 至 -0.4%）。
与 75 毫升瓶相比，在家中饮用 50 毫升瓶装葡萄酒可能会减少饮酒量和饮酒速度。
