State Key Laboratory of Military Stomatology & National Clinical Research Center for Oral Diseases & Shaanxi Key Laboratory of Stomatology, Department of Prosthodontics, School of Stomatology, The Fourth Military Medical University, Xi'an, 710032, Shaanxi, China.
College of Graduate Studies, Augusta University, Augusta, GA, 30912, USA.
Adv Mater. 2020 Jun;32(22):e1907833. doi: 10.1002/adma.201907833. Epub 2020 Apr 9.
Microbe-mediated mineralization is ubiquitous in nature, involving bacteria, fungi, viruses, and algae. These mineralization processes comprise calcification, silicification, and iron mineralization. The mechanisms for mineral formation include extracellular and intracellular biomineralization. The mineral precipitating capability of microbes is often harnessed for green synthesis of metal nanoparticles, which are relatively less toxic compared with those synthesized through physical or chemical methods. Microbe-mediated mineralization has important applications ranging from pollutant removal and nonreactive carriers, to other industrial and biomedical applications. Herein, the different types of microbe-mediated biomineralization that occur in nature, their mechanisms, as well as their applications are elucidated to create a backdrop for future research.
微生物介导的矿化作用在自然界中普遍存在，涉及细菌、真菌、病毒和藻类。这些矿化过程包括钙化、硅化和铁矿化。矿物形成的机制包括细胞外和细胞内生物矿化。微生物的矿物沉淀能力常被用于金属纳米粒子的绿色合成，与通过物理或化学方法合成的纳米粒子相比，其毒性相对较低。微生物介导的矿化作用在从污染物去除和非反应性载体到其他工业和生物医学应用等领域具有重要应用。本文阐述了自然界中发生的不同类型的微生物介导的生物矿化作用、其机制以及它们的应用，为未来的研究创造了背景。
