Zhu Yao, Ye Dingwei
Department of Urology, Fudan University Shanghai Cancer Center, Shanghai, People's Republic of China.
Department of Oncology, Shanghai Medical School, Fudan University, Shanghai, People's Republic of China.
Cancer Manag Res. 2020 Mar 23;12:2127-2140. doi: 10.2147/CMAR.S236879. eCollection 2020.
Currently, the basic treatment of advanced prostate cancer is still endocrine therapy, but almost all patients eventually progress to castration-resistant prostate cancer (CRPC). In 2016, the Chinese Expert Consensus on the Diagnosis and Treatment of CRPC which aimed to help Chinese clinicians formulate treatment plans for CRPC was published. In this 2019 update, the 2016 version was updated with the aim of providing a more appropriate reference for clinical practice, standardizing CRPC patient management, and facilitating decision-making. The consensus is evidence-based and reviews the optimal therapeutic recommendations for CRPC management in China by taking into consideration the clinical characteristics of Chinese patients; drug availability, efficacy and safety; and recent advancements and developments in the international medical arena.
目前,晚期前列腺癌的基本治疗方法仍是内分泌治疗,但几乎所有患者最终都会进展为去势抵抗性前列腺癌(CRPC)。2016年,旨在帮助中国临床医生制定CRPC治疗方案的《中国CRPC诊断与治疗专家共识》发布。在本次2019年更新中,对2016年版本进行了更新,目的是为临床实践提供更合适的参考,规范CRPC患者管理,并促进决策制定。该共识基于循证医学,通过考虑中国患者的临床特征、药物可及性、疗效和安全性以及国际医学领域的最新进展,对中国CRPC管理的最佳治疗建议进行了综述。