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SARS-CoV-2, the Virus that Causes COVID-19: Cytometry and the New Challenge for Global Health.严重急性呼吸综合征冠状病毒2（SARS-CoV-2），即导致2019冠状病毒病（COVID-19）的病毒：细胞计数法与全球健康面临的新挑战
Cytometry A. 2020 Apr;97(4):340-343. doi: 10.1002/cyto.a.24002. Epub 2020 Mar 18.
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Aerosol and Surface Stability of SARS-CoV-2 as Compared with SARS-CoV-1.与严重急性呼吸综合征冠状病毒1（SARS-CoV-1）相比，严重急性呼吸综合征冠状病毒2（SARS-CoV-2）在气溶胶和表面的稳定性
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Emergence of a Novel Coronavirus, Severe Acute Respiratory Syndrome Coronavirus 2: Biology and Therapeutic Options.新型冠状病毒的出现：严重急性呼吸系统综合征冠状病毒 2：生物学和治疗选择。
J Clin Microbiol. 2020 Apr 23;58(5). doi: 10.1128/JCM.00187-20.
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Detection of SARS-CoV-2 in Different Types of Clinical Specimens.SARS-CoV-2 在不同类型临床标本中的检测。
JAMA. 2020 May 12;323(18):1843-1844. doi: 10.1001/jama.2020.3786.
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The epidemiology and pathogenesis of coronavirus disease (COVID-19) outbreak.冠状病毒病（COVID-19）疫情的流行病学和发病机制。
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SARS-CoV-2 Viral Load in Upper Respiratory Specimens of Infected Patients.感染患者上呼吸道标本中的新型冠状病毒2型病毒载量
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A pneumonia outbreak associated with a new coronavirus of probable bat origin.一种新型冠状病毒引发的肺炎疫情，该病毒可能来源于蝙蝠。
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Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China.中国武汉地区 2019 年新型冠状病毒感染患者的临床特征。
Lancet. 2020 Feb 15;395(10223):497-506. doi: 10.1016/S0140-6736(20)30183-5. Epub 2020 Jan 24.
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Current gaps in sepsis immunology: new opportunities for translational research.脓毒症免疫学的当前差距：转化研究的新机遇。
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Comprehensive Phenotyping of T Cells Using Flow Cytometry.使用流式细胞术进行全面的 T 细胞表型分析。
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处理和检测 COVID-19 患者的血液样本，以安全地研究细胞表型和细胞因子风暴。

Handling and Processing of Blood Specimens from Patients with COVID-19 for Safe Studies on Cell Phenotype and Cytokine Storm.

机构信息

Department of Medical and Surgical Sciences for Children and Adults, School of Medicine, University of Modena and Reggio Emilia, Modena, Italy.

National Institute for Cardiovascular Research, Bologna, Italy.

出版信息

Cytometry A. 2020 Jul;97(7):668-673. doi: 10.1002/cyto.a.24009. Epub 2020 Apr 10.

DOI:10.1002/cyto.a.24009
PMID:32275124
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7262259/
Abstract

The pandemic caused by severe acute respiratory syndrome coronavirus 2 heavily involves all those working in a laboratory. Samples from known infected patients or donors who are considered healthy can arrive, and a colleague might be asymptomatic but able to transmit the virus. Working in a clinical laboratory is posing several safety challenges. Few years ago, International Society for Advancement of Cytometry published guidelines to safely analyze and sort human samples that were revised in these days. We describe the procedures that we have been following since the first patient appeared in Italy, which have only slightly modified our standard one, being all human samples associated with risks. © 2020 International Society for Advancement of Cytometry.

摘要

由严重急性呼吸综合征冠状病毒 2 引起的大流行严重涉及到所有在实验室工作的人。可能会收到来自已知感染患者或被认为健康的供体的样本，而且同事可能无症状但能够传播病毒。在临床实验室工作带来了一些安全挑战。几年前，国际细胞分析学会发布了安全分析和分选人类样本的指南，并在最近进行了修订。我们描述了自第一个意大利患者出现以来我们一直遵循的程序，这些程序仅对我们的标准程序进行了微小的修改，因为所有与人相关的样本都存在风险。© 2020 国际细胞分析学会。