School of Biosciences and Veterinary Medicine, University of Camerino, Via Gentile III Da Varano, I-62032 Camerino, MC, Italy.
School of Biosciences and Veterinary Medicine, University of Camerino, Via Gentile III Da Varano, I-62032 Camerino, MC, Italy.
Mar Pollut Bull. 2020 Apr;153:111012. doi: 10.1016/j.marpolbul.2020.111012. Epub 2020 Feb 25.
The present study sought to determine bioaccumulation and potential molecular effects of four of the most environmentally significant sunscreen agents in juvenile loggerhead sea turtles (Caretta caretta) from the Italian coasts of the central Adriatic Sea. Each of these sunscreen agents were found in most of the plasma samples analyzed, with benzophenone-3 as the dominant species. Total concentrations of the sunscreen agents ranged from not detected (<LOD) to 28.43 μg mL. Almost all of the gene biomarkers of inflammation, oxidative stress and hormonal activity assessed by RT-qPCR in blood tissue showed significant positive correlations with total sunscreen agent concentrations. The present study is the first to provide data on contamination by sunscreen agents in loggerheads, and indicates that these chemicals tend to bioaccumulate and exert potential adverse effects in sea turtles.
本研究旨在确定 4 种最具环境意义的防晒霜成分在来自意大利亚得里亚海中部海岸的幼年红海龟（Caretta caretta）体内的生物累积情况和潜在的分子效应。在分析的大多数血浆样本中均发现了这 4 种防晒霜成分，其中二苯甲酮-3 为主要成分。防晒霜成分的总浓度范围从未检出（<LOD）至 28.43μg/mL。通过 RT-qPCR 在血液组织中评估的几乎所有炎症、氧化应激和激素活性的基因生物标志物与总防晒霜成分浓度均呈显著正相关。本研究首次提供了红海龟受防晒霜成分污染的数据，并表明这些化学物质易于在海龟体内生物累积，并产生潜在的不良影响。
