部分抗生素去污
Partial antibiotic decontamination.
作者信息
Guiot H F, Furth R
出版信息
Br Med J. 1977 Mar 26;1(6064):800-2. doi: 10.1136/bmj.1.6064.798-a.
Abstract
Partial antibiotic decontamination and reverse isolation were carried out in nine patients undergoing bone marrow transplantation. The aim of this approach was to eradicate the patient's endogenous potentially pathogenic bacteria while preserving the anaerobic flora of the gut, which help to prevent recolonisation. No exogenous infections developed, and only one patient developed an infection associated with endogenous recolonisation. Colonisation resistance seemed normal in patients during partial antibiotic decontamination. This form of decontamination deserves further study in patients with immunodepression.
摘要
对9例接受骨髓移植的患者进行了部分抗生素去污和反向隔离。这种方法的目的是根除患者体内潜在的病原菌，同时保留肠道厌氧菌丛，以帮助防止再次定植。未发生外源性感染，仅有1例患者发生了与内源性再定植相关的感染。在部分抗生素去污期间，患者的定植抗力似乎正常。这种去污形式值得在免疫抑制患者中进一步研究。
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