Laker-Oketta Miriam, Butler Lisa, Kadama-Makanga Philippa, Inglis Robert, Wenger Megan, Katongole-Mbidde Edward, Maurer Toby, Kambugu Andrew, Martin Jeffrey
Infectious Diseases Institute, Makerere University, Kampala, Uganda.
University of Connecticut, Storrs, CT, USA.
J Oncol. 2020 Mar 21;2020:3254820. doi: 10.1155/2020/3254820. eCollection 2020.
Despite its hallmark cutaneous presentation, most Kaposi's sarcoma (KS) in Africa is diagnosed too late for effective treatment. Early diagnosis will only be achievable if patients with KS present earlier for care. We hypothesized that public awareness about KS can be enhanced through exposure to common media.
We developed educational messages regarding early detection of KS for the general African public portraying a three-part theme: "Look" (regularly examine one's skin/mouth), "Show" (bring to the attention of a healthcare provider any skin/mouth changes), and "Test" (ask for a biopsy for definitive diagnosis). We packaged the messages in three common media forms (comic strips, radio, and video) and tested their effect on increasing KS awareness among adults attending markets in Uganda. Participants were randomized to a single exposure to one of the media and evaluated for change in KS-related knowledge and attitudes.
Among 420 participants, media exposure resulted in increased ability to identify KS (from 0.95% pretest to 46% posttest); awareness that anyone is at risk for KS (29% to 50%); belief that they may be at risk (63% to 76%); and knowledge that definitive diagnosis requires biopsy (23% to 51%) (all < 0.001). Most participants (96%) found the media culturally appropriate.
Exposure to media featuring a theme of "Look," "Show," and "Test" resulted in changes in knowledge and attitudes concerning KS among the general public in Uganda. High incidence and poor survival of KS in Africa are an impetus to further evaluate these media, which are freely available online.
尽管卡波西肉瘤（KS）具有典型的皮肤表现，但非洲大多数KS患者确诊时已为时过晚，无法进行有效治疗。只有当KS患者更早就诊时，才能实现早期诊断。我们推测，通过接触常见媒体可以提高公众对KS的认识。
我们为非洲普通公众制定了关于KS早期检测的教育信息，呈现了一个三部分主题：“看”（定期检查自己的皮肤/口腔）、“展示”（将任何皮肤/口腔变化告知医疗服务提供者）和“检测”（要求进行活检以明确诊断）。我们将这些信息包装成三种常见媒体形式（连环漫画、广播和视频），并测试它们对提高乌干达市场成年人群体对KS认识的效果。参与者被随机分配单次接触其中一种媒体，并评估他们在KS相关知识和态度方面的变化。
在420名参与者中，媒体接触使识别KS的能力有所提高（从测试前的0.95%提高到测试后的46%）；认识到任何人都有患KS的风险（从29%提高到50%）；相信自己可能有风险（从63%提高到76%）；以及了解明确诊断需要活检（从23%提高到51%）（所有P<0.001）。大多数参与者（96%）认为这些媒体在文化上是合适的。
接触以“看”、“展示”和“检测”为主题的媒体，使乌干达普通公众在KS相关知识和态度上发生了变化。非洲KS的高发病率和低生存率促使我们进一步评估这些可在网上免费获取的媒体。
