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对儿童荨麻疹病因发病机制的贡献。

Contribution to the etiopathogenesis of urticaria in children.

作者信息

Moreno M V, González de la Cuesta C, Oehling A

机构信息

Department of Allergology, Faculty of Medicine, University of Navarra, Pamplona, Spain.

出版信息

Allergol Immunopathol (Madr). 1988 Jul-Aug;16(4):225-30.

PMID:3228042
Abstract

For hundreds of years urticaria has been an intriguing problem for researchers. Together with angioedema it constitutes a common condition that affects 20% of the general population. The etiologic diagnosis is obtained in a variable percentage of cases, according to the different studies published. The clinical course and the association with angioedema are also variables in the different works. It was the diversity of results that led us to undertake the present study. We selected 161 histories of children who came to our department of allergology; these children whose ages ranged from 1-12 years were diagnosed of urticaria and/or angio edema. The number of males was slightly higher than females and the most affected age group was that between 7-12 years. The acute and acute intermittent forms predominated especially in atopic children, highly associated with angioedema; chronic urticaria was less frequent. Within the etiologic factors, food allergy played an important role, followed by drug allergy. It was not possible to reach an etiologic diagnosis in 39.13% of cases.

摘要

数百年来,荨麻疹一直是困扰研究人员的一个有趣问题。它与血管性水肿共同构成一种常见病症,影响着20%的普通人群。根据已发表的不同研究,病因诊断在不同比例的病例中得以确定。在不同的研究中,临床病程以及与血管性水肿的关联情况也各不相同。正是结果的多样性促使我们开展了本研究。我们选取了161例前来我院过敏科就诊的儿童病例;这些年龄在1至12岁之间的儿童被诊断患有荨麻疹和/或血管性水肿。男性人数略多于女性,受影响最严重的年龄组是7至12岁。急性和急性间歇性形式尤为常见,特别是在特应性儿童中,且与血管性水肿高度相关;慢性荨麻疹则较为少见。在病因方面,食物过敏起了重要作用,其次是药物过敏。在39.13%的病例中无法做出病因诊断。

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