Agrochemical Research Group, Chemical Program, School of Exact and Natural Sciences, University of Cartagena, Cartagena, Colombia.
Doctoral Program in Environmental Toxicology, School of Pharmaceutical Sciences, University of Cartagena, Cartagena, Bolivar, Colombia.
PLoS One. 2020 Apr 13;15(4):e0231310. doi: 10.1371/journal.pone.0231310. eCollection 2020.
Shrimps can be used as indicators of the quality of aquatic systems exposed to a variety of pollutants. Chlorpyrifos is one of the most common pesticides found in environmental samples. In order to evaluate the effects of chlorpyrifos, adult organisms of Litopenaeus vannamei were exposed to two sublethal concentrations of the pesticide (0.7 and 1.3 μg/L) for four days. The LC50 (96-hours) value was determined and Lipid oxidation levels (LPO) and the activities of catalase (CAT), glutathion peroxidase (GPx), glutathion-S-transferase (GST) were assessed on the muscle, hepatopancreas and gills from the exposed organisms. In addition, inhibition of acetylcholinesterase (AChE) was determined in the brain. LC50 (96-hours) was 2.10 μg/L of chlorpyrifos. Catalase activity and LPO were elevated in the three tissues, whereas a decrease of AChE activities in the brain and an increase of GST activity in the hepatopancreas were observed.
虾可以作为暴露于各种污染物的水生态系统质量的指示物。毒死蜱是环境样本中最常见的农药之一。为了评估毒死蜱的影响，将凡纳滨对虾的成年个体暴露于两种亚致死浓度的农药（0.7 和 1.3μg/L）中四天。测定了 LC50（96 小时）值，并评估了肌肉、肝胰腺和鳃中脂质氧化水平（LPO）以及过氧化氢酶（CAT）、谷胱甘肽过氧化物酶（GPx）和谷胱甘肽-S-转移酶（GST）的活性。此外，还测定了脑内乙酰胆碱酯酶（AChE）的抑制作用。LC50（96 小时）为 2.10μg/L 的毒死蜱。CAT 活性和 LPO 在三种组织中升高，而大脑中的 AChE 活性下降，肝胰腺中的 GST 活性升高。
