Pambuccian Stefan E
Department of Pathology and Laboratory Medicine, Loyola University Medical Center, Maywood, Illinois.
J Am Soc Cytopathol. 2020 May-Jun;9(3):202-211. doi: 10.1016/j.jasc.2020.03.001. Epub 2020 Mar 26.
The coronavirus disease 2019 (COVID-19) is a pandemic caused by the SARS-CoV-2 virus. The infection has predominantly respiratory transmission and is transmitted through large droplets or aerosols, and less commonly by contact with infected surfaces or fomites. The alarming spread of the infection and the severe clinical disease that it may cause have led to the widespread institution of social distancing measures. Because of repeated exposure to potentially infectious patients and specimens, health care and laboratory personnel are particularly susceptible to contract COVID-19. This review paper provides an assessment of the current state of knowledge about the disease and its pathology, and the potential presence of the virus in cytology specimens. It also discusses the measures that cytology laboratories can take to function during the pandemic, and minimize the risk to their personnel, trainees, and pathologists. In addition, it explores potential means to continue to educate trainees during the COVID-19 pandemic.
2019年冠状病毒病(COVID-19)是由严重急性呼吸综合征冠状病毒2(SARS-CoV-2)引起的大流行病。该感染主要通过呼吸道传播,经大飞沫或气溶胶传播,较少通过接触受感染的表面或污染物传播。该感染令人震惊的传播速度以及它可能导致的严重临床疾病,已促使社会广泛采取社交距离措施。由于反复接触潜在感染性患者和标本,医护人员和实验室人员尤其容易感染COVID-19。这篇综述文章评估了关于该疾病及其病理学的当前知识状况,以及病毒在细胞学标本中的潜在存在情况。它还讨论了细胞学实验室在大流行期间可以采取的运作措施,并将其人员、学员和病理学家面临的风险降至最低。此外,它探讨了在COVID-19大流行期间继续培训学员的潜在方法。