Rawlins J N, Maxwell T J, Sinden J D
University of Oxford, Department of Experimental Psychology, U.K.
Behav Brain Res. 1988 Nov 1;31(1):17-28. doi: 10.1016/0166-4328(88)90154-4.
Two groups of rats were trained in 2-lever operant tasks that required them to follow either a Win-shift/Lose-stay rule, or else a Win-stay/Lose-shift rule. The rats in each testing condition attained a similar level of performance. Once the tasks had been learnt, half of the rats in each testing condition were given fornix lesions. These lesions produced a clear performance impairment at all inter-response retention intervals tested in those rats trained on the Win-shift/Lose-stay task, but impaired performance in rats trained on the Win-stay/Lose-shift condition only when the inter-response interval reached 10 s. The implications of these results for the working memory theory and for the temporal discontiguity theory are discussed.
两组大鼠接受双杠杆操作性任务训练，要求它们遵循赢则转换/输则停留规则，或者赢则停留/输则转换规则。每种测试条件下的大鼠都达到了相似的表现水平。一旦学会任务，每种测试条件下的一半大鼠接受穹窿损伤。这些损伤在接受赢则转换/输则停留任务训练的大鼠所测试的所有反应间保持间隔中均产生了明显的表现损伤，但仅当反应间间隔达到10秒时，才会损害接受赢则停留/输则转换条件训练的大鼠的表现。本文讨论了这些结果对工作记忆理论和时间不连续性理论的意义。
