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属的特征：耐药机制与炎症性肠病

The Characterization of Genus: Resistance Mechanisms and Inflammatory Bowel Disease.

作者信息

Růžičková Michaela, Vítězová Monika, Kushkevych Ivan

机构信息

Department of Experimental Biology, Faculty of Science, Masaryk University, Kamenice 753/5, 625 00 Brno, Czech Republic.

出版信息

Open Med (Wars). 2020 Apr 3;15:211-224. doi: 10.1515/med-2020-0032. eCollection 2020.

DOI:10.1515/med-2020-0032
PMID:32292819
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7147287/
Abstract

The constantly growing bacterial resistance against antibiotics is recently causing serious problems in the field of human and veterinary medicine as well as in agriculture. The mechanisms of resistance formation and its preventions are not well explored in most bacterial genera. The aim of this review is to analyse recent literature data on the principles of antibiotic resistance formation in bacteria of the genus. Furthermore, the habitat of the genus, its pathogenicity and pathogenicity factors, its epidemiology, genetic and molecular aspects of antibiotic resistance, and the relationship between these bacteria and bowel diseases are discussed. So-called VREfm - vancomycin resistant and its currently rapidly growing resistance as well as the significance of these bacteria in nosocomial diseases is described.

摘要

细菌对抗生素的耐药性不断增强，这一问题近来在人类医学、兽医学以及农业领域引发了严重困扰。在大多数细菌属中，耐药性形成机制及其预防方法尚未得到充分研究。本综述旨在分析近期有关该属细菌抗生素耐药性形成原理的文献数据。此外，还讨论了该属细菌的栖息地、致病性及致病因素、流行病学、抗生素耐药性的遗传和分子层面，以及这些细菌与肠道疾病之间的关系。文中描述了所谓的耐万古霉素屎肠球菌（VREfm）及其目前迅速增长的耐药性，以及这些细菌在医院感染性疾病中的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8abf/7147287/688c093dac16/med-15-211-g007.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8abf/7147287/27f3df65de91/med-15-211-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8abf/7147287/bf9745577897/med-15-211-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8abf/7147287/2e94d754a634/med-15-211-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8abf/7147287/8534267e316d/med-15-211-g004.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8abf/7147287/688c093dac16/med-15-211-g007.jpg

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