警惕细胞因子风暴：COVID-19 的免疫病理学。
On the Alert for Cytokine Storm: Immunopathology in COVID-19.
机构信息
Boston Children's Hospital and Harvard Medical School, Boston, Massachusetts.
UPMC Children's Hospital of Pittsburgh and University of Pittsburgh, Pittsburgh, Pennsylvania.
出版信息
Arthritis Rheumatol. 2020 Jul;72(7):1059-1063. doi: 10.1002/art.41285. Epub 2020 May 10.
Abstract
Poor outcomes in COVID-19 correlate with clinical and laboratory features of cytokine storm syndrome. Broad screening for cytokine storm and early, targeted antiinflammatory therapy may prevent immunopathology and could help conserve limited health care resources. While studies are ongoing, extrapolating from clinical experience in cytokine storm syndromes may benefit the multidisciplinary teams caring for patients with severe COVID-19.
摘要
COVID-19 患者的预后不良与细胞因子风暴综合征的临床和实验室特征相关。广泛筛查细胞因子风暴并早期进行靶向抗炎治疗可能预防免疫病理，有助于节约有限的医疗资源。虽然相关研究正在进行，但从细胞因子风暴综合征的临床经验推断，可能有助于为治疗严重 COVID-19 患者的多学科团队提供帮助。
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