Department of Neurology, University of Virginia, Charlottesville, Virginia.
Department of Pediatrics, University of Colorado, Aurora, Colorado.
Semin Neurol. 2020 Apr;40(2):192-200. doi: 10.1055/s-0040-1703000. Epub 2020 Apr 15.
Multiple sclerosis is being increasingly recognized and diagnosed in children. In the past several years, advances have been made in diagnosing multiple sclerosis in children, identifying new genetic and environmental risk factors, delineating underlying immunobiology, characterizing imaging findings, and implementing new treatment strategies. In this review, we discuss these advances. Future research into the determinants of multiple sclerosis in children and into new treatment options will be aided by continued international collaboration.
多发性硬化症在儿童中越来越被认识和诊断。在过去的几年中，儿童多发性硬化症的诊断、新的遗传和环境风险因素的识别、潜在免疫生物学的描述、影像学表现的特征以及新的治疗策略的实施都取得了进展。在这篇综述中，我们讨论了这些进展。对儿童多发性硬化症决定因素和新治疗选择的未来研究将得益于持续的国际合作。
