Reginato Elena, Azzolina Danila, Folino Franco, Valentini Romina, Bendinelli Camilla, Gafare Claudia Elena, Cainelli Elisa, Vedovelli Luca, Iliceto Sabino, Gregori Dario, Lorenzoni Giulia
Unit of Biostatistics, Epidemiology and Public Health, Department of Cardiac, Thoracic, Vascular Sciences and Public Health, University of Padova, Via Loredan, 18, 35131 Padova, Italy.
Department of Translational Medicine, University of Eastern Piedmont, 28100 Novara, Italy.
J Clin Med. 2020 Apr 14;9(4):1121. doi: 10.3390/jcm9041121.
Assessment of heart rate variability (HRV) and cardiac ectopic beats is a clinically relevant topic. The present exploratory observational study aimed to inspect the relationships of lifestyle, dietary patterns, and anthropometrics with HRV, premature ventricular complexes (PVCs), and supraventricular premature complexes (SVPCs). A cross-sectional study enrolling subjects undergoing Holter monitoring was performed. Sociodemographic and clinical characteristics, body composition (full-body bio-impedentiometry), dietary patterns (validated food frequency questionnaire and 24 h dietary recall), and quality of life were assessed. Generalized additive models were estimated to evaluate the relationships between outcomes of interest and variables collected. The study enrolled 121 consecutive patients undergoing 24 h Holter monitoring. Upon univariable analysis, HRV was found to have an inverse association with mass of body fat (MBF) (-value 0.015), while doing physical activity was associated with a significantly higher HRV (-value 0.036). Upon multivariable analysis, fruit consumption in the 24 h dietary recall was found to be directly associated with HRV (-value 0.044). The present findings might be useful for improving the management of patients attending cardiac rhythm labs, and to tailor ad hoc prevention strategies (modification of lifestyle and eating habits) based on Holter parameters.
心率变异性（HRV）和心脏异位搏动的评估是一个具有临床相关性的课题。本探索性观察性研究旨在探讨生活方式、饮食模式和人体测量学与HRV、室性早搏（PVC）和室上性早搏（SVPC）之间的关系。进行了一项纳入接受动态心电图监测受试者的横断面研究。评估了社会人口统计学和临床特征以及身体成分（全身生物电阻抗分析）、饮食模式（经过验证的食物频率问卷和24小时饮食回顾）和生活质量。估计广义相加模型以评估感兴趣的结果与所收集变量之间的关系。该研究纳入了121名连续接受24小时动态心电图监测的患者。单变量分析发现，HRV与体脂量（MBF）呈负相关（P值0.015），而进行体育活动与显著更高的HRV相关（P值0.036）。多变量分析发现，24小时饮食回顾中的水果摄入量与HRV直接相关（P值0.044）。本研究结果可能有助于改善心律实验室就诊患者的管理，并根据动态心电图参数制定专门的预防策略（改变生活方式和饮食习惯）。
