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黄粉虫幼虫蜕皮作为一种用于BALB/c小鼠肠道微生物群的新型益生元材料。

Mealworm larvae ( L.) exuviae as a novel prebiotic material for BALB/c mouse gut microbiota.

作者信息

Kwon Gyoo Taik, Yuk Hyun-Gyun, Lee Su Jung, Chung Yi Hyung, Jang Han Su, Yoo Jong-Sang, Cho Kyung-Hoon, Kong Hyunseok, Shin Daekeun

机构信息

Berry and Biofood Research Institute, Gochang, Republic of Korea.

2Department of Food Science and Technology, Korea National University of Transportation, Jeungpyeong-gun, Chungbuk Republic of Korea.

出版信息

Food Sci Biotechnol. 2019 Dec 23;29(4):531-537. doi: 10.1007/s10068-019-00699-1. eCollection 2020 Apr.

Abstract

The objective of this study was to evaluate the effect of yellow mealworm ( L.) exuviae (ME) given as a prebiotic in 20% of the diet fed to BALB/c mice. Analysis of the ME revealed that it was mostly composed of crude protein (52.94%), crude fiber (10.70%), and moisture (10.54%). When ME was fed to mice for 8 weeks, the number of intestinal lactic acid bacteria increased, reaching similar numbers (4.50 ± 0.80 CFU/mL) to those (4.70 ± 0.80 CFU/mL) of the control group not fed ME. Microbiome analysis showed that 8 weeks feeding of ME promoted the growth of and compared to the POS group, indicating the positive effects of feeding 20% ME on the intestinal microbiota of mice. These results suggest that ME can be considered as a dietary prebiotics to improve human gut microbial population, but further application study to human is necessary.

摘要

本研究的目的是评估将黄粉虫(L.)蜕皮(ME)作为益生元添加到喂食BALB/c小鼠的20%日粮中的效果。对ME的分析表明,它主要由粗蛋白(52.94%)、粗纤维(10.70%)和水分(10.54%)组成。当给小鼠喂食ME 8周时,肠道乳酸菌数量增加,达到与未喂食ME的对照组(4.70±0.80 CFU/mL)相似的数量(4.50±0.80 CFU/mL)。微生物组分析表明,与POS组相比,喂食ME 8周促进了 和 的生长,表明喂食20%ME对小鼠肠道微生物群有积极影响。这些结果表明,ME可被视为一种膳食益生元,以改善人类肠道微生物群,但有必要对人类进行进一步的应用研究。

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