Department of Orthoptics and Visual Sciences, School of Health Sciences, International University of Health and Welfare, Tochigi, Japan.
Sanno Hospital, Tokyo, Japan.
Sci Rep. 2020 Apr 16;10(1):6501. doi: 10.1038/s41598-020-63546-y.
A new method is developed and validated for intraocular lens (IOL) power calculation based on paraxial ray tracing of the postoperative IOL positions, which are obtained with the use of anterior segment optical coherence tomography. Of the 474 eyes studied, 137 and 337 were grouped into training and validation sets, respectively. The positions of the implanted IOLs of the training datasets were characterized with multiple linear regression analyses one month after the operations. A new regression formula was developed to predict the postoperative anterior chamber depth with the use of the stepwise analysis results. In the validation dataset, postoperative refractive values were calculated according to the paraxial ray tracing of the cornea and lens based on the assumption of finite structural thicknesses with separate surface curvatures. The predicted refraction error was calculated as the difference of the expected postoperative refraction from the spherical-equivalent objective refraction values. The percentage error (within ±0.50 diopters) of the new formula was 84.3%. This was not significantly correlated to the axial length or keratometry. The developed formula yielded excellent postoperative refraction predictions and could be applicable to eyes with abnormal proportions, such as steep or flat corneal curvatures and short and long axial lengths.
一种新的方法被开发并验证用于基于术后人工晶状体位置的傍轴光线追踪的人工晶状体（IOL）功率计算，这些位置是使用前节光学相干断层扫描获得的。在研究的 474 只眼中，137 只和 337 只分别分为训练集和验证集。手术后一个月，使用多元线性回归分析对训练数据集的植入人工晶状体位置进行特征描述。利用逐步分析结果开发了一种新的回归公式来预测术后前房深度。在验证数据集中，根据角膜和晶状体的傍轴光线追踪，基于独立表面曲率的有限结构厚度假设，计算术后屈光值。预测的屈光误差被计算为预期术后屈光与球镜等效客观屈光值的差异。新公式的百分比误差（在±0.50 屈光度内）为 84.3%。这与眼轴长度或角膜曲率计没有显著相关性。开发的公式产生了出色的术后屈光预测效果，可适用于比例异常的眼睛，如陡峭或平坦的角膜曲率和短或长的眼轴长度。
