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本文引用的文献

1
Overtreatment in the United States.美国的过度治疗。
PLoS One. 2017 Sep 6;12(9):e0181970. doi: 10.1371/journal.pone.0181970. eCollection 2017.
2
UK clinical guideline for the prevention and treatment of osteoporosis.英国临床指南:骨质疏松症的预防和治疗。
Arch Osteoporos. 2017 Dec;12(1):43. doi: 10.1007/s11657-017-0324-5. Epub 2017 Apr 19.
3
[Excessive osteoporosis screening in women under 65 years: a cross-sectional study].[65岁以下女性骨质疏松症过度筛查:一项横断面研究]
Salud Colect. 2016 Jul-Sep;12(3):443-452. doi: 10.18294/sc.2016.841.
4
Communicating about overdiagnosis: Learning from community focus groups on osteoporosis.关于过度诊断的沟通:从骨质疏松症社区焦点小组中学习。
PLoS One. 2017 Feb 3;12(2):e0170142. doi: 10.1371/journal.pone.0170142. eCollection 2017.
5
Clinicians' Expectations of the Benefits and Harms of Treatments, Screening, and Tests: A Systematic Review.临床医生对治疗、筛查和检测的获益和危害的期望:系统评价。
JAMA Intern Med. 2017 Mar 1;177(3):407-419. doi: 10.1001/jamainternmed.2016.8254.
6
Osteoporosis Overtreatment in a Regional Health Care System.区域医疗系统中的骨质疏松症过度治疗
JAMA Intern Med. 2016 Mar;176(3):391-3. doi: 10.1001/jamainternmed.2015.6020.
7
Overuse and Underuse of Antiosteoporotic Treatments According to Highly Influential Osteoporosis Guidelines: A Population-Based Cross-Sectional Study in Spain.根据极具影响力的骨质疏松症指南评估抗骨质疏松治疗的过度使用和使用不足情况:西班牙一项基于人群的横断面研究
PLoS One. 2015 Aug 28;10(8):e0135475. doi: 10.1371/journal.pone.0135475. eCollection 2015.
8
Cost-effective osteoporosis treatment thresholds in Greece.希腊具有成本效益的骨质疏松症治疗阈值。
Osteoporos Int. 2015 Jul;26(7):1949-57. doi: 10.1007/s00198-015-3055-8. Epub 2015 Mar 5.
9
Patients' expectations of the benefits and harms of treatments, screening, and tests: a systematic review.患者对治疗、筛查和检测的获益和风险的期望:系统评价。
JAMA Intern Med. 2015 Feb;175(2):274-86. doi: 10.1001/jamainternmed.2014.6016.
10
The osteoporosis treatment gap.骨质疏松症治疗缺口。
J Bone Miner Res. 2014 Sep;29(9):1926-8. doi: 10.1002/jbmr.2301.

抗骨质疏松治疗起始情况的评估:希腊的一项回顾性观察研究。

Assessment of the antiosteoporotic treatment initiation: A retrospective observational study in Greece.

作者信息

Rizou Stavroula, Aravantinos Leon, Paganas Aristofanis, Ballas Michael, Lyritis George P

机构信息

Hellenic Osteoporosis Foundation, Athens, Greece.

2 Department of Obstetrics and Gynecology, University of Athens, Aretaieion Hospital, Athens, Greece.

出版信息

J Frailty Sarcopenia Falls. 2017 Dec 1;2(4):78-82. doi: 10.22540/JFSF-02-078. eCollection 2017 Dec.

DOI:10.22540/JFSF-02-078
PMID:32300684
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7155366/
Abstract

OBJECTIVE

A study to retrospectively assess the decision to implement treatment for osteoporosis based on Greek version of FRAX tool.

METHODS

The study population was 1000 postmenopausal women aged 45 or above, excluding those with medical conditions demanding specific osteoporosis management. Data were collected regarding their medical history and additionally, risk factors incorporated in FRAX questionnaire. FRAX score was estimated at the time of the anti-osteoporotic treatment initiation.

RESULTS

The mean age of the study sample was 58.5±8.79 years. 46.8% of the participating osteopenic women had initiated treatment for osteoporosis at their first consultation while the 80.6% met the current national intervention threshold of FRAX tool.

CONCLUSION

Stemming from our results there is an indication that women who are borderline eligible for treatment and seek consultation for osteoporosis are likely to be given treatment regardless of the potential benefit. One cannot ignore the fact that a clinician's good clinical judgment is of the utmost importance and under no circumstances can be replaced by any prognostic assessment tool.

摘要

目的

一项回顾性研究,旨在基于FRAX工具的希腊语版本评估骨质疏松症治疗决策。

方法

研究人群为1000名45岁及以上的绝经后女性,排除患有需要特定骨质疏松症管理的疾病的女性。收集她们的病史数据,此外,还收集FRAX问卷中包含的风险因素。在开始抗骨质疏松治疗时估算FRAX评分。

结果

研究样本的平均年龄为58.5±8.79岁。46.8%的参与研究的骨量减少女性在首次咨询时就开始了骨质疏松症治疗,而80.6%的女性达到了FRAX工具当前的国家干预阈值。

结论

从我们的结果来看,有迹象表明,处于治疗边缘且寻求骨质疏松症咨询的女性无论潜在益处如何都可能接受治疗。不能忽视这样一个事实,即临床医生良好的临床判断至关重要,在任何情况下都不能被任何预后评估工具所取代。