Department of Investigational Cancer Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Department of Thoracic/Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Adv Exp Med Biol. 2020;1244:255-269. doi: 10.1007/978-3-030-41008-7_13.
Checkpoint inhibitors are part of the family of immunotherapies and are increasingly being used in a wide variety of cancers. Immune-related adverse events pose a major challenge in the treatment of cancer patients. Pneumonitis is a rare immune-related adverse event that presents in distinct patterns. The goal of this chapter is to instruct readers on the incidence and clinical manifestations of pneumonitis and to offer guidance in the evaluation and treatment of patients with pneumonitis.
检查点抑制剂是免疫疗法家族的一部分,越来越多地用于多种癌症的治疗。免疫相关不良事件是癌症患者治疗中的主要挑战。肺炎是一种罕见的免疫相关不良事件,具有不同的表现形式。本章的目的是指导读者了解肺炎的发生率和临床表现,并为肺炎患者的评估和治疗提供指导。