Jensen N H, Dragsted L, Christensen J K, Jørgensen J C, Qvist J
Department of Anaesthesia and Intensive Care, Herlev Hospital, Copenhagen, Denmark.
Intensive Care Med. 1988;15(1):19-22. doi: 10.1007/BF00255630.
To study whether critically ill alcoholics were more sick and had a worse outcome than other patients treated in the intensive care unit, data were collected during the initial 24 h on 216 consecutive patients admitted to an intensive care unit. Twentysix patients (12%) met the criteria for alcohol abuse. The patients' chronic health 6 months prior to admission and the extent of physiological derangement (Acute Physiology Score and Chronic Health Evaluation (APACHE] were recorded just as the type and amount of treatment (Therapeutic Intervention Scoring System (TISS]. Alcoholics were found to be significantly more sick and had a higher mortality (50% compared to 26%) than other critically ill patients. However, when analyzing the TISS points, no difference was found between the two groups. All survivors were, every third month up to 1 year after admission, asked to fill in a questionnaire indicating their level of activity. No differences were found between the two groups 1 year after admission, but the alcoholics had lost more time due to death. It is concluded that studies with larger number of patients will reveal whether alcoholics constitute a special category of patients with a different prognosis than other ICU patients.
为研究重症酒精中毒患者是否比重症监护病房（ICU）中接受治疗的其他患者病情更重且预后更差，我们收集了连续入住某ICU的216例患者最初24小时内的数据。26例患者（12%）符合酒精滥用标准。记录患者入院前6个月的慢性健康状况、生理紊乱程度（急性生理学评分和慢性健康评估（APACHE））以及治疗类型和治疗量（治疗干预评分系统（TISS））。结果发现，与其他重症患者相比，酒精中毒患者病情明显更重，死亡率更高（分别为50%和26%）。然而，分析TISS评分时，两组之间未发现差异。所有幸存者在入院后直至1年期间，每3个月会被要求填写一份问卷，说明其活动水平。入院1年后，两组之间未发现差异，但酒精中毒患者因死亡而损失的时间更多。结论是，纳入更多患者的研究将揭示酒精中毒患者是否构成一类与其他ICU患者预后不同的特殊患者群体。
