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重症监护病房中酒精性患者的疾病严重程度及治疗结果

Severity of illness and outcome of treatment in alcoholic patients in the intensive care unit.

作者信息

Jensen N H, Dragsted L, Christensen J K, Jørgensen J C, Qvist J

机构信息

Department of Anaesthesia and Intensive Care, Herlev Hospital, Copenhagen, Denmark.

出版信息

Intensive Care Med. 1988;15(1):19-22. doi: 10.1007/BF00255630.

Abstract

To study whether critically ill alcoholics were more sick and had a worse outcome than other patients treated in the intensive care unit, data were collected during the initial 24 h on 216 consecutive patients admitted to an intensive care unit. Twentysix patients (12%) met the criteria for alcohol abuse. The patients' chronic health 6 months prior to admission and the extent of physiological derangement (Acute Physiology Score and Chronic Health Evaluation (APACHE] were recorded just as the type and amount of treatment (Therapeutic Intervention Scoring System (TISS]. Alcoholics were found to be significantly more sick and had a higher mortality (50% compared to 26%) than other critically ill patients. However, when analyzing the TISS points, no difference was found between the two groups. All survivors were, every third month up to 1 year after admission, asked to fill in a questionnaire indicating their level of activity. No differences were found between the two groups 1 year after admission, but the alcoholics had lost more time due to death. It is concluded that studies with larger number of patients will reveal whether alcoholics constitute a special category of patients with a different prognosis than other ICU patients.

摘要

为研究重症酒精中毒患者是否比重症监护病房(ICU)中接受治疗的其他患者病情更重且预后更差,我们收集了连续入住某ICU的216例患者最初24小时内的数据。26例患者(12%)符合酒精滥用标准。记录患者入院前6个月的慢性健康状况、生理紊乱程度(急性生理学评分和慢性健康评估(APACHE))以及治疗类型和治疗量(治疗干预评分系统(TISS))。结果发现,与其他重症患者相比,酒精中毒患者病情明显更重,死亡率更高(分别为50%和26%)。然而,分析TISS评分时,两组之间未发现差异。所有幸存者在入院后直至1年期间,每3个月会被要求填写一份问卷,说明其活动水平。入院1年后,两组之间未发现差异,但酒精中毒患者因死亡而损失的时间更多。结论是,纳入更多患者的研究将揭示酒精中毒患者是否构成一类与其他ICU患者预后不同的特殊患者群体。

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