College of Life Sciences and Medicine, Zhejiang Sci-Tech University, Hangzhou, 310018, China; Department of Chemistry, University of Limpopo, Private Bag X1106, Sovenga, 0727, Polokwane, South Africa.
College of Life Sciences and Medicine, Zhejiang Sci-Tech University, Hangzhou, 310018, China; Horticulture Department, Faculty of Agriculture, Al-Azhar University, Nasr City, Cairo, 11651, Egypt.
J Ethnopharmacol. 2020 Jul 15;257:112879. doi: 10.1016/j.jep.2020.112879. Epub 2020 Apr 16.
Cordyceps cicadae (Mig.) Massee is one of the oldest and well-known traditional Chinese medicine (TCM), with its uses recorded as far back as the 5th century A.D. For centuries, C. cicadae has been used as food, tonic and folk medicine to treat malaria, palpitations, cancer, fever, diabetes, eye diseases, dizziness, and chronic kidney diseases. Although C. cicadae has been used as TCM for over 1600 years, it is not the most popular amongst the Cordyceps family. Cordyceps Sinensis (C. sinensis) and Cordyceps militaris (C. militaris) are the most studied and widely used, with a number of commercially available products derived from these two Cordyceps species.
This review seeks to look at the research that has been conducted on C. cicadae over the past 30 years, reporting on the biological activities, development and utilization. This information was compared to that focused on C. sinensis and C. militaris.
A literature search was conducted on different scientific search engines including, but not limited to "Web of Science", "ScienceDirect" and "Google Scholar" to identify published data on C. cicadae, I. cicadae, P. cicadae, C. sinensis and C. militaris.
Research conducted on C. cicadae over the past two decades have shown that it poses similar biological properties and chemical composition as C. sinensis and C. militaris. C. cicadae has been reported to grow in many geographic locations, as compared to C. sinensis, and can be artificially cultivated via different methods.
There exists sufficient evidence that C. cicadae has medicinal benefits and contain bioactive compounds similar to those found on C. sinensis and C. militaris. However, more research and standardization methods are still needed to directly compare C. cicadae with C. sinensis and C. militaris, in order to ascertain the suitability of C. cicadae as an alternative source of Cordyceps products.
蝉花（Mig.）Massee 是中国最古老和著名的传统中药（TCM）之一，其用途可追溯到公元 5 世纪。几个世纪以来，蝉花一直被用作食物、补品和民间药物，用于治疗疟疾、心悸、癌症、发热、糖尿病、眼病、头晕和慢性肾病。尽管蝉花已被用作 TCM 超过 1600 年，但它并不是虫草属家族中最受欢迎的一种。蛹虫草（C. sinensis）和北虫草（C. militaris）是研究和应用最广泛的两种虫草，有许多商业化的产品来源于这两种虫草。
本综述旨在回顾过去 30 年来对蝉花的研究，报告其生物活性、开发和利用情况。并将这些信息与蛹虫草和北虫草的研究情况进行比较。
在不同的科学搜索引擎上进行文献检索，包括但不限于“Web of Science”、“ScienceDirect”和“Google Scholar”，以确定关于蝉花、蝉拟青霉、蛹虫草、蛹虫草和北虫草的已发表数据。
过去二十年对蝉花的研究表明，它具有与蛹虫草和北虫草相似的生物特性和化学成分。与蛹虫草相比，蝉花被报道生长在许多地理区域，并且可以通过不同的方法进行人工栽培。
有足够的证据表明蝉花具有药用功效，并含有与蛹虫草和北虫草相似的生物活性化合物。然而，为了确定蝉花作为虫草产品替代来源的适宜性，仍需要更多的研究和标准化方法来直接比较蝉花与蛹虫草和北虫草。
