Aghagoli Ghazal, Gallo Marin Benjamin, Soliman Luke B, Sellke Frank W
Warren Alpert Medical School of Brown University, Providence, Rhode Island.
Division of Cardiothoracic Surgery, Rhode Island Hospital, Providence, Rhode Island.
J Card Surg. 2020 Jun;35(6):1302-1305. doi: 10.1111/jocs.14538. Epub 2020 Apr 19.
Respiratory complications have been well remarked in the novel coronavirus disease (SARS-CoV-2/COVID-19), yet an emerging body of research indicates that cardiac involvement may be implicated in poor outcomes for these patients.
This review seeks to gather and distill the existing body of literature that describes the cardiac implications of COVID-19.
The English literature was reviewed for papers dealing with the cardiac effects of COVID-19.
Notably, COVID-19 patients with pre-existing cardiovascular disease are counted in greater frequency in intensive care unit settings, and ultimately suffer greater rates of mortality. Other studies have noted cardiac presentations for COVID-19, rather than respiratory, such as acute pericarditis and left ventricular dysfunction. In some patients there has been evidence of acute myocardial injury, with correspondingly increased serum troponin I levels. With regard to surgical interventions, there is a dearth of data describing myocardial protection during cardiac surgery for COVID-19 patients. Although some insights have been garnered in the study of cardiovascular diseases for these patients, these insights remain fragmented and have yet to cement clear guidelines for actionable clinical practice.
While some information is available, further studies are imperative for a more cohesive understanding of the cardiac pathophysiology in COVID-19 patients to promote more informed treatment and, ultimately, better clinical outcomes.
新型冠状病毒病(SARS-CoV-2/COVID-19)中的呼吸并发症已广为人知,但越来越多的研究表明,心脏受累可能与这些患者的不良预后有关。
本综述旨在收集和提炼现有的文献,这些文献描述了COVID-19对心脏的影响。
对英文文献进行综述,以查找有关COVID-19心脏影响的论文。
值得注意的是,在重症监护病房中,患有心血管疾病的COVID-19患者更为常见,最终死亡率更高。其他研究指出,COVID-19患者的心脏表现而非呼吸表现,如急性心包炎和左心室功能障碍。在一些患者中,有急性心肌损伤的证据,血清肌钙蛋白I水平相应升高。关于手术干预,缺乏描述COVID-19患者心脏手术期间心肌保护的数据。尽管在这些患者的心血管疾病研究中已经获得了一些见解,但这些见解仍然零散,尚未形成明确的可操作临床实践指南。
虽然已有一些信息,但仍需进一步研究,以便更全面地了解COVID-19患者的心脏病理生理学,从而促进更明智的治疗,并最终改善临床结果。