Department of Pharmacology, Institute of Biology, Rio de Janeiro State University, Rio de Janeiro, Brazil.
Hypertens Pregnancy. 2020 May;39(2):211-219. doi: 10.1080/10641955.2020.1754850. Epub 2020 Apr 18.
: To investigate whether Euterpe oleracea Mart. (açaí) seed extract (ASE) prevents maternal cardiovascular changes and intrauterine growth restriction (IUGR) in experimental preeclampsia (PE).: ASE administration (200 mg/kg/day) during mid to late pregnancy in a rat model of L-NAME-induced PE.: ASE impaired the maternal hypertension and microalbuminuria as well as the lower fetal and placental weight in experimental PE. ASE also prevented the maternal vascular dysfunction and lipoperoxidation in this model.: ASE protected against maternal cardiovascular changes and IUGR in the L-NAME-induced PE. The protective effect of ASE may be partly explained by its antioxidant property.
: 研究紫玉盘（黑老虎）籽油（ASE）是否可以预防实验性子痫前期（PE）中的母体心血管变化和宫内生长受限（IUGR）。: 在 L-NAME 诱导的 PE 大鼠模型中，在妊娠中期至晚期给予 ASE（200mg/kg/天）。: ASE 可改善母体高血压和微量白蛋白尿，以及降低实验性 PE 中的胎儿和胎盘重量。ASE 还可预防该模型中的母体血管功能障碍和脂质过氧化。: ASE 可预防 L-NAME 诱导的 PE 中的母体心血管变化和 IUGR。ASE 的保护作用可能部分归因于其抗氧化特性。
