Peng Wen, Liu Yami, Wang Cheng
Department of Orthopaedic Surgery, The First Affiliated Hospital, Hengyang Medical School, University of South China, Hengyang, China.
Foshan Orthopedic Implant (Stable) Engineering Technology Research Center, Foshan, China.
Front Bioeng Biotechnol. 2023 Jan 4;10:1081548. doi: 10.3389/fbioe.2022.1081548. eCollection 2022.
Bioengineered porous bone tissue materials based on additive manufacturing technology have gradually become a research hotspot in bone tissue-related bioengineering. Research on structural design, preparation and processing processes, and performance optimization has been carried out for this material, and further industrial translation and clinical applications have been implemented. However, based on previous studies, there is controversy in the academic community about characterizing the pore structure dimensions of porous materials, with problems in the definition logic and measurement method for specific parameters. In addition, there are significant differences in the specific morphological and functional concepts for the pore structure due to differences in defining the dimensional characterization parameters of the pore structure, leading to some conflicts in perceptions and discussions among researchers. To further clarify the definitions, measurements, and dimensional parameters of porous structures in bioengineered bone materials, this literature review analyzes different dimensional characterization parameters of pore structures of porous materials to provide a theoretical basis for unified definitions and the standardized use of parameters.
基于增材制造技术的生物工程多孔骨组织材料已逐渐成为骨组织相关生物工程领域的研究热点。针对该材料开展了结构设计、制备加工工艺及性能优化等方面的研究，并进一步实现了产业转化和临床应用。然而，基于以往研究，学术界在多孔材料孔隙结构尺寸表征方面存在争议，具体参数的定义逻辑和测量方法存在问题。此外，由于孔隙结构尺寸表征参数定义的差异，孔隙结构在具体形态和功能概念上存在显著差异，导致研究人员之间在认识和讨论上出现一些冲突。为进一步明确生物工程骨材料中多孔结构的定义、测量方法及尺寸参数，本文献综述分析了多孔材料孔隙结构的不同尺寸表征参数，为参数的统一定义和规范使用提供理论依据。
