Ogilvie Patricia, Thulesen Jesper, Leys Christophe, Sykianakis Dimitris, Chantrey Jonquille, Safa Marva, Figueiredo Vitor, Heydenrych Izolda, Cavallini Maurizio, Langeland Elin Kringen, Wetter Anne
SkinConcept, Munich, Germany.
Clinic Aesthetica, Copenhagen, Denmark.
Clin Cosmet Investig Dermatol. 2020 Apr 5;13:267-274. doi: 10.2147/CCID.S239667. eCollection 2020.
VYC-12L is a hyaluronic acid (HA) injectable gel designed to treat fine cutaneous lines and improve skin quality attributes such as hydration and elasticity.
Expert consensus was sought on VYC-12L injection technique and primary treatment target areas.
A multinational group of aesthetic medicine clinicians (n = 128) attended product training and each identified ~10 patients for VYC-12L. After treating their first and last patients, the clinicians completed a survey on preferred injection methodology/technique, including injection angle, volume, and spacing. An expert panel (n = 12) discussed survey results and their clinical experiences to obtain consensus on VYC-12L technique and appropriate treatment areas.
Recommendations included micro-depot injections of VYC-12L into the deep dermis with a 32G ½ inch needle inserted at <45º to the skin, spaced 0.5‒1.0 cm apart, with 0.01‒0.05 mL volume per injection (full-face total volume: ~2 mL). Recommended primary treatment areas were the malar, perioral, neck, and décolletage regions. Injection techniques for different treatment areas/demographic characteristics were similar, with some variability in treatment approach. Patient selection criteria, pre- and post-treatment guidelines, and managing patient expectations are important components of treatment.
These consensus recommendations may assist clinicians in optimizing the treatment of fine lines with VYC-12L.
VYC - 12L是一种透明质酸（HA）可注射凝胶，旨在治疗皮肤细纹并改善皮肤质量属性，如保湿和弹性。
就VYC - 12L注射技术和主要治疗目标区域寻求专家共识。
一组来自多个国家的美容医学临床医生（n = 128）参加了产品培训，每人确定约10名患者接受VYC - 12L治疗。在治疗他们的第一名和最后一名患者后，临床医生完成了一项关于首选注射方法/技术的调查，包括注射角度、剂量和间距。一个专家小组（n = 12）讨论了调查结果及其临床经验，以就VYC - 12L技术和合适的治疗区域达成共识。
建议包括使用32G ½英寸针头以小于45°的角度插入皮肤，将VYC - 12L微注射到真皮深层，注射点间距为0.5 - 1.0厘米，每次注射量为0.01 - 0.05毫升（全脸总量：约2毫升）。推荐的主要治疗区域是颧骨、口周、颈部和胸部。不同治疗区域/人口统计学特征的注射技术相似，但治疗方法存在一些差异。患者选择标准、治疗前和治疗后指南以及管理患者期望是治疗的重要组成部分。
这些共识建议可能有助于临床医生优化使用VYC - 12L治疗细纹。
