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慢性摄入甘草导致的伴有严重低钾血症和横纹肌溶解的四肢轻瘫

Tetraparesis with Major Hypokalaemia and Rhabdomyolysis Induced by Chronic Liquorice Ingestion.

作者信息

Attout Hassene, Randriajohany Andry, Josse Françoise, Appavoupoule Vincent, Thirapathi Yoga

出版信息

Eur J Case Rep Intern Med. 2020 Mar 9;7(4):001375. doi: 10.12890/2020_001375. eCollection 2020.

Abstract

UNLABELLED

Chronic ingestion of liquorice induces a syndrome with findings similar to those for primary hyperaldosteronism. This is characterized by hypokalaemia, hypertension, metabolic alkalosis and suppression of the renin-aldosterone system. We describe a 30-year-old woman who, with a plasma potassium level of 1.5 mmol/l, presented with tetraparesis and severe rhabdomyolysis (CK up to 35,460 U/l). She admitted to a daily consumption of nearly 300 g of liquorice sweets during the previous 6 months. This case emphasizes the importance of a detailed anamnesis, which is essential for diagnosis, avoids unnecessary and expensive investigations and reduces the duration of hospitalization.

LEARNING POINTS

Liquorice, the root of , has been used throughout the millennia for its taste and for medicinal purposes.Chronic ingestion of liquorice can mimic primary hyperaldosteronism.It is important for physicians to keep liquorice consumption in mind as a cause of hypokalaemic paralysis and rhabdomyolysis.

摘要

未标注

长期摄入甘草会引发一种综合征,其表现与原发性醛固酮增多症相似。其特征为低钾血症、高血压、代谢性碱中毒以及肾素 - 醛固酮系统受抑制。我们描述了一名30岁女性,其血浆钾水平为1.5 mmol/L,出现四肢轻瘫和严重横纹肌溶解(肌酸激酶高达35460 U/L)。她承认在过去6个月中每天食用近300克甘草糖。该病例强调了详细问诊的重要性,这对诊断至关重要,可避免不必要且昂贵的检查,并缩短住院时间。

学习要点

甘草,即甘草的根,数千年来因其味道和药用价值而被使用。长期摄入甘草可模拟原发性醛固酮增多症。医生应牢记甘草摄入是低钾性麻痹和横纹肌溶解的一个病因。

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