Department of Otolaryngology-Head and Neck Surgery, Medical University of South Carolina, Charleston, South Carolina, USA.
Head Neck. 2020 Sep;42(9):2308-2315. doi: 10.1002/hed.26172. Epub 2020 Apr 21.
There is a paucity of information regarding the incidence and survival of parotid malignancies over time.
The Surveillance, Epidemiology, and End Results population-based cancer registry was queried for parotid malignancies from 1973 to 2015.
The age-adjusted incidence of parotid malignancies has increased by 58.1% (7.87-12.44 per 1 000 000). Analysis of histologic type revealed an increased annual percent change (APC) of acinar cell carcinoma (1.38) and squamous cell carcinoma (1.58), but decreased APC of adenoid cystic carcinoma (-1.63) and adenocarcinoma NOS (-0.86) (P < .05). The disease-specific survival of mucoepidermoid carcinoma, adenocarcinoma NOS, and squamous cell carcinoma significantly improved (P < .05) over time.
The incidence of parotid cancer is rising steadily since 1973, while the incidence of overall head and neck cancer has decreased. Further research is necessary to understand the etiology, risk factors, and pathophysiology of parotid cancer to curb its rising incidence.
关于腮腺恶性肿瘤随时间推移的发病率和生存率的信息较少。
通过监测、流行病学和最终结果（SEER）基于人群的癌症登记处，从 1973 年到 2015 年对腮腺恶性肿瘤进行了查询。
年龄调整后的腮腺恶性肿瘤发病率增加了 58.1%（7.87-12.44/100 万）。对组织学类型的分析显示，腺泡细胞癌（1.38）和鳞状细胞癌（1.58）的年百分比变化率（APC）增加，但腺样囊性癌（-1.63）和腺癌 NOS（-0.86）的 APC 降低（P<.05）。黏液表皮样癌、腺癌 NOS 和鳞状细胞癌的疾病特异性生存率随时间显著改善（P<.05）。
自 1973 年以来，腮腺癌的发病率一直在稳步上升，而头颈部癌症的总体发病率却在下降。需要进一步研究以了解腮腺癌的病因、危险因素和病理生理学，以遏制其发病率的上升。
4 级
